This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8fak
From Proteopedia
(Difference between revisions)
m (Protected "8fak" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli== | |
| - | + | <StructureSection load='8fak' size='340' side='right'caption='[[8fak]], [[Resolution|resolution]] 3.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8fak]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FAK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fak OCA], [https://pdbe.org/8fak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fak RCSB], [https://www.ebi.ac.uk/pdbsum/8fak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fak ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Blumenthal | + | [https://www.uniprot.org/uniprot/PRIB_ECOLI PRIB_ECOLI] Binds single-stranded DNA at the primosome assembly site (PAS). During primosome assembly it facilitates the complex formation between PriA and DnaT.<ref>PMID:1856227</ref> <ref>PMID:1646811</ref> <ref>PMID:8366072</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Grant | + | </StructureSection> |
| - | [[Category: Larson | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| + | [[Category: Blumenthal KH]] | ||
| + | [[Category: Deorio HR]] | ||
| + | [[Category: Duckworth AT]] | ||
| + | [[Category: Ducos PL]] | ||
| + | [[Category: Grant T]] | ||
| + | [[Category: Keck JL]] | ||
| + | [[Category: Larson JA]] | ||
| + | [[Category: McMillan SD]] | ||
| + | [[Category: Sandler SJ]] | ||
| + | [[Category: Satyshur KA]] | ||
Current revision
DNA replication fork binding triggers structural changes in the PriA DNA helicase that regulate the PriA-PriB replication restart pathway in E. coli
| |||||||||||
