4kzs

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Current revision (12:16, 1 March 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kzs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_R046Wa Helicobacter pylori R046Wa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KZS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kzs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_R046Wa Helicobacter pylori R046Wa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KZS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzs OCA], [https://pdbe.org/4kzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kzs RCSB], [https://www.ebi.ac.uk/pdbsum/4kzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kzs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzs OCA], [https://pdbe.org/4kzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kzs RCSB], [https://www.ebi.ac.uk/pdbsum/4kzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kzs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/K2KM35_HELPX K2KM35_HELPX]
[https://www.uniprot.org/uniprot/K2KM35_HELPX K2KM35_HELPX]
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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HP1454 is a protein of 303 amino acids found in the extracellular milieu of Helicobacter pylori. The protein structure, crystallized in the orthorhombic C2221 space group with one molecule per asymmetric unit, has been determined using the SAD method. HP1454 exhibits an elongated bent shape, composed of three distinct domains. Each domain possesses a fold already present in other structures: domain I contains a three-strand antiparallel beta-barrel flanked by a long alpha-helix, domain II is an anti-parallel three-helix bundle, and domain III a beta-sheet flanked by two alpha-helices. The overall assembly of the protein does not bear any similarity with known structures. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc.
 
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Crystal structure of the secreted protein HP1454 from the human pathogen Helicobacter pylori.,Quarantini S, Cendron L, Zanotti G Proteins. 2014 May 23. doi: 10.1002/prot.24608. PMID:24854568<ref>PMID:24854568</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 4kzs" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Current revision

Crystal structure of the secreted protein HP1454 from the human pathogen Helicobacter pylori

PDB ID 4kzs

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