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8bv8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the phage Mu protein Mom inactive mutant S124A== | |
| - | + | <StructureSection load='8bv8' size='340' side='right'caption='[[8bv8]], [[Resolution|resolution]] 2.03Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8bv8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_Mu Escherichia phage Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BV8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bv8 OCA], [https://pdbe.org/8bv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bv8 RCSB], [https://www.ebi.ac.uk/pdbsum/8bv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bv8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MOM_BPMU MOM_BPMU] Iron-binding protein that performs methylcarbamoylation of adenine using acetyl CoA (PubMed:32369169). This chemical modificaltion makes the viral DNA resistant to a variety of host type I and type II restriction enzymes by modifying approximately 15% of DNA adenine residues (PubMed:32369169). The modification called momylation changes adenine for N6-methylcarbamoyl adenine and occurs just before packaging (PubMed:1258376, PubMed:32369169). Target sequences are 5'-(C or G)-A-(Cor G)-N-(C or T)-3' (PubMed:1258376). Also usually modifies adenine residues in the host cellular DNA (PubMed:1258376).<ref>PMID:1258376</ref> <ref>PMID:32369169</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia phage Mu]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bochtler M]] | ||
| + | [[Category: Guan C]] | ||
| + | [[Category: Lee YJ]] | ||
| + | [[Category: Lund SR]] | ||
| + | [[Category: Raleigh EA]] | ||
| + | [[Category: Silva RMB]] | ||
| + | [[Category: Skowronek K]] | ||
| + | [[Category: Slyvka A]] | ||
| + | [[Category: Weigele PR]] | ||
Current revision
Crystal structure of the phage Mu protein Mom inactive mutant S124A
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Categories: Escherichia phage Mu | Large Structures | Bochtler M | Guan C | Lee YJ | Lund SR | Raleigh EA | Silva RMB | Skowronek K | Slyvka A | Weigele PR
