8bxt
From Proteopedia
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(New page: '''Unreleased structure''' The entry 8bxt is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of StayGold== | |
| + | <StructureSection load='8bxt' size='340' side='right'caption='[[8bxt]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8bxt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cytaeis_uchidae Cytaeis uchidae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BXT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CR2:{(4Z)-2-(AMINOMETHYL)-4-[(4-HYDROXYPHENYL)METHYLIDENE]-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>CR2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bxt OCA], [https://pdbe.org/8bxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bxt RCSB], [https://www.ebi.ac.uk/pdbsum/8bxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bxt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A8S0GSD4_9CNID A0A8S0GSD4_9CNID] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | StayGold is an exceptionally bright and stable fluorescent protein that is highly resistant to photobleaching. Despite favorable fluorescence properties, use of StayGold as a fluorescent tag is limited because it forms a natural dimer. Here we report the 1.6 A structure of StayGold and generate a derivative, mStayGold, that retains the brightness and photostability of the original protein while being fully monomeric. | ||
| - | + | A monomeric StayGold fluorescent protein.,Ivorra-Molla E, Akhuli D, McAndrew MBL, Scott W, Kumar L, Palani S, Mishima M, Crow A, Balasubramanian MK Nat Biotechnol. 2024 Sep;42(9):1368-1371. doi: 10.1038/s41587-023-02018-w. Epub , 2023 Dec 11. PMID:38081970<ref>PMID:38081970</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8bxt" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cytaeis uchidae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Akhuli D]] | ||
| + | [[Category: Crow A]] | ||
| + | [[Category: Ivorra-Molla E]] | ||
Current revision
Structure of StayGold
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