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8c0s
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8c0s is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of S. aureus BlaR1 sensor domain in complex with an imidazole inhibitor== | |
| - | + | <StructureSection load='8c0s' size='340' side='right'caption='[[8c0s]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8c0s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C0S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SYU:3-[[2,4-bis(trifluoromethyl)phenyl]methyl]-5-(hydroxymethyl)-1~{H}-imidazole-2-thione'>SYU</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c0s OCA], [https://pdbe.org/8c0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c0s RCSB], [https://www.ebi.ac.uk/pdbsum/8c0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c0s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLAR_STAAU BLAR_STAAU] BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Hermoso JA]] | ||
| + | [[Category: Miguel-Ruano V]] | ||
Current revision
Crystal structure of S. aureus BlaR1 sensor domain in complex with an imidazole inhibitor
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