8fm9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer== | |
| + | <StructureSection load='8fm9' size='340' side='right'caption='[[8fm9]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8fm9]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Flock_House_virus Flock House virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FM9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fm9 OCA], [https://pdbe.org/8fm9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fm9 RCSB], [https://www.ebi.ac.uk/pdbsum/8fm9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fm9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RDRP_FHV RDRP_FHV] RNA-dependent RNA polymerase, which replicates the viral genome composed of 2 RNA segments, RNA1 and RNA2 (Probable). Does not need an exogenous primer (PubMed:24466277). Also possesses a terminal nucleotidyl transferase (TNTase) activity (PubMed:24466277). The TNTase catalyzes the addition of nucleotide to the 3'-end of plus- and minus-stranded RNAs, probably to repair the 3'-end nucleotide loss (PubMed:24466277). Forms the open necked connection to the cytosol of the virus-induced replication vesicles (PubMed:32690711, PubMed:36560715, PubMed:36693094). Mediates viral RNA1 recruitment (PubMed:17301137).<ref>PMID:17301137</ref> <ref>PMID:24466277</ref> <ref>PMID:32690711</ref> <ref>PMID:36560715</ref> <ref>PMID:36693094</ref> <ref>PMID:24466277</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Flock House virus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ahlquist P]] | ||
| + | [[Category: Broadberry R]] | ||
| + | [[Category: Grant T]] | ||
| + | [[Category: Horswill M]] | ||
| + | [[Category: Myers J]] | ||
| + | [[Category: Pennington J]] | ||
| + | [[Category: Rebolledo Viveros A]] | ||
| + | [[Category: Unchwaniwala N]] | ||
| + | [[Category: Zhan H]] | ||
| + | [[Category: Den Boon J]] | ||
Current revision
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
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