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8fe5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of J-PKAc chimera complexed with Aplithianine B== | |
| - | + | <StructureSection load='8fe5' size='340' side='right'caption='[[8fe5]], [[Resolution|resolution]] 2.51Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8fe5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FE5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FE5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=XTT:6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one'>XTT</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fe5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fe5 OCA], [https://pdbe.org/8fe5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fe5 RCSB], [https://www.ebi.ac.uk/pdbsum/8fe5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fe5 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Dalilian M]] |
| - | [[Category: | + | [[Category: Du L]] |
| - | [[Category: | + | [[Category: Goncharova EI]] |
| + | [[Category: Li N]] | ||
| + | [[Category: Martinez Fiesco JA]] | ||
| + | [[Category: O'Keefe BR]] | ||
| + | [[Category: Smith EA]] | ||
| + | [[Category: Wamiru A]] | ||
| + | [[Category: Wang D]] | ||
| + | [[Category: Wilson BAP]] | ||
| + | [[Category: Zhang P]] | ||
Current revision
Structure of J-PKAc chimera complexed with Aplithianine B
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Categories: Homo sapiens | Large Structures | Dalilian M | Du L | Goncharova EI | Li N | Martinez Fiesco JA | O'Keefe BR | Smith EA | Wamiru A | Wang D | Wilson BAP | Zhang P
