8hk3
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==C3aR-Gi-apo protein complex== | |
- | + | <StructureSection load='8hk3' size='340' side='right'caption='[[8hk3]], [[Resolution|resolution]] 3.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8hk3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HK3 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hk3 OCA], [https://pdbe.org/8hk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hk3 RCSB], [https://www.ebi.ac.uk/pdbsum/8hk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hk3 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Bos taurus]] | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Rattus norvegicus]] | ||
+ | [[Category: Liu W]] | ||
+ | [[Category: Wang Y]] | ||
+ | [[Category: Xu HE]] | ||
+ | [[Category: Xu Y]] | ||
+ | [[Category: Zhuang Y]] |
Current revision
C3aR-Gi-apo protein complex
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Categories: Bos taurus | Homo sapiens | Large Structures | Rattus norvegicus | Liu W | Wang Y | Xu HE | Xu Y | Zhuang Y