This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8c3j
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Stapled peptide SP2 in complex with humanised RadA mutant HumRadA22== | |
| - | + | <StructureSection load='8c3j' size='340' side='right'caption='[[8c3j]], [[Resolution|resolution]] 3.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8c3j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C3J FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.02Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TKI:2-[(4,6-diethyl-1,3,5-triazin-2-yl)-methyl-amino]ethanoic+acid'>TKI</scene></td></tr> |
| - | [[Category: Hyvonen | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c3j OCA], [https://pdbe.org/8c3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c3j RCSB], [https://www.ebi.ac.uk/pdbsum/8c3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c3j ProSAT]</span></td></tr> |
| - | [[Category: Pantelejevs | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pyrococcus furiosus]] | ||
| + | [[Category: Hyvonen M]] | ||
| + | [[Category: Pantelejevs T]] | ||
Current revision
Stapled peptide SP2 in complex with humanised RadA mutant HumRadA22
| |||||||||||
