LDL receptor
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 22: | Line 22: | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *hLDLR ligand-binding domain | + | *hLDLR ligand-binding domain;Repeats - LB1 20-67; LB2 55-104; LB4 144-195; LB5 196-232; LB6 234-272; LB7 274-313 |
**[[1ldl]] – hLDLR LB1 - human - NMR<br /> | **[[1ldl]] – hLDLR LB1 - human - NMR<br /> | ||
| Line 41: | Line 41: | ||
**[[5oy9]] – hLDLR LBD LB3 + glycoprotein G<br /> | **[[5oy9]] – hLDLR LBD LB3 + glycoprotein G<br /> | ||
| - | *hLDLR EGFP | + | *hLDLR EGFP domain 263-699 |
**[[1ijq]] – hLDLR YWTD-EGF<br /> | **[[1ijq]] – hLDLR YWTD-EGF<br /> | ||
| Line 54: | Line 54: | ||
**[[2w2n]], [[3gcw]] – hLDLR EGF1, EGF2 (mutant) + proprotein convertase subtilisin/kexin 9<br /> | **[[2w2n]], [[3gcw]] – hLDLR EGF1, EGF2 (mutant) + proprotein convertase subtilisin/kexin 9<br /> | ||
| - | *hLDLR cytoplasmic domain | + | *hLDLR cytoplasmic domain C terminal 817-832 |
**[[3so6]] – hLDLR C terminal + LDLR adaptor protein<br /> | **[[3so6]] – hLDLR C terminal + LDLR adaptor protein<br /> | ||
| - | *hLDLR lectin-like domain | + | *hLDLR lectin-like domain 136-273 |
| + | **[[1ypo]], [[1ypq]], [[1ypu]], [[7w5d]], [[7xmp]] – hLDLR<br /> | ||
**[[3vlg]] – hLDLR (mutant)<br /> | **[[3vlg]] – hLDLR (mutant)<br /> | ||
Current revision
| |||||||||||
3D structures of LDL receptor
Updated on 10-July-2024
References
- ↑ Goldstein JL, Brown MS. The LDL receptor. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):431-8. doi:, 10.1161/ATVBAHA.108.179564. PMID:19299327 doi:http://dx.doi.org/10.1161/ATVBAHA.108.179564
- ↑ Mak YT, Pang CP, Tomlinson B, Zhang J, Chan YS, Mak TW, Masarei JR. Mutations in the low-density lipoprotein receptor gene in Chinese familial hypercholesterolemia patients. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1600-5. PMID:9763532
