8hoy
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram== | |
| - | + | <StructureSection load='8hoy' size='340' side='right'caption='[[8hoy]], [[Resolution|resolution]] 2.76Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hoy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HOY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.76Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hoy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hoy OCA], [https://pdbe.org/8hoy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hoy RCSB], [https://www.ebi.ac.uk/pdbsum/8hoy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hoy ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOL_MONPV DPOL_MONPV] Catalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral OPG148 and OPG116 proteins, thereby forming the DNA polymerase holoenzyme. Displays 3'- to 5' exonuclease activity. Might participate in viral DNA recombination. Does not perform OPG116/D4synthesis across an abasic site.[UniProtKB:P06856] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Monkeypox virus]] | ||
| + | [[Category: Dong C]] | ||
| + | [[Category: Fan R]] | ||
| + | [[Category: Li D]] | ||
| + | [[Category: Wu Y]] | ||
| + | [[Category: Xu Y]] | ||
| + | [[Category: Yang B]] | ||
| + | [[Category: Yang Y]] | ||
| + | [[Category: Zhang Y]] | ||
| + | [[Category: Zhang Z]] | ||
Current revision
Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram
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Categories: Large Structures | Monkeypox virus | Dong C | Fan R | Li D | Wu Y | Xu Y | Yang B | Yang Y | Zhang Y | Zhang Z
