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8fx5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline== | |
| + | <StructureSection load='8fx5' size='340' side='right'caption='[[8fx5]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8fx5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FX5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XNO:xanomeline'>XNO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fx5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fx5 OCA], [https://pdbe.org/8fx5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fx5 RCSB], [https://www.ebi.ac.uk/pdbsum/8fx5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fx5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. | ||
| - | + | ==See Also== | |
| - | + | *[[Transducin 3D structures|Transducin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Glukhova | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Danev R]] |
| - | [[Category: | + | [[Category: Glukhova A]] |
| - | [[Category: | + | [[Category: Mobbs JI]] |
| + | [[Category: Sexton PM]] | ||
| + | [[Category: Thal DM]] | ||
| + | [[Category: Vuckovic Z]] | ||
Current revision
Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline
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Categories: Homo sapiens | Large Structures | Mus musculus | Danev R | Glukhova A | Mobbs JI | Sexton PM | Thal DM | Vuckovic Z
