This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Heat Shock Protein structures
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 29: | Line 29: | ||
**[[4ylb]], [[4ylc]] - SsHsp20 (mutant)<br /> | **[[4ylb]], [[4ylc]] - SsHsp20 (mutant)<br /> | ||
**[[5z81]] – VcHsp15 – ''Vibrio cholerae''<br /> | **[[5z81]] – VcHsp15 – ''Vibrio cholerae''<br /> | ||
| + | **[[4i2n]] – VcHsp31<br /> | ||
**[[3bbu]] – EcHsp15 - ''Escherichia coli'' – Cryo-EM<br /> | **[[3bbu]] – EcHsp15 - ''Escherichia coli'' – Cryo-EM<br /> | ||
| + | **[[1dm9]] – EcHsp15<br /> | ||
| + | **[[8ap4]] – EcHsp15 in 50S ribosome – Cryo-EM<br /> | ||
**[[1ons]] – EcHsp31<br /> | **[[1ons]] – EcHsp31<br /> | ||
**[[3gla]], [[3gt6]], [[3guf]] – Hsp – ''Xanthomonas axonopodis''<br /> | **[[3gla]], [[3gt6]], [[3guf]] – Hsp – ''Xanthomonas axonopodis''<br /> | ||
| - | **[[3vqk]] – StHsp14 – ''Sulfolobus tokodaii''<br /> | + | **[[3aac]], [3vqk]] – StHsp14 – ''Sulfolobus tokodaii''<br /> |
| - | **[[3vql]], [[3vqm]] – StHsp14 (mutant)<br /> | + | **[[3aab]], [[3vql]], [[3vqm]] – StHsp14 (mutant)<br /> |
**[[3w1z]] – Hsp16 – ''Schizosacchromyces pombe''<br /> | **[[3w1z]] – Hsp16 – ''Schizosacchromyces pombe''<br /> | ||
**[[5j7n]] – Hsp – ''Xylella fastidiosa''<br /> | **[[5j7n]] – Hsp – ''Xylella fastidiosa''<br /> | ||
| + | **[[6l6m]] – Hsp18.5 – ''Entamoeba histolytica''<br /> | ||
| + | **[[4fei]] – Hsp17.7 – ''Deinococcus radiodurans''<br /> | ||
**[[1shs]], [[4eld]], [[4i88]] – Hsp – ''Methanococcus jannaschii''<br /> | **[[1shs]], [[4eld]], [[4i88]] – Hsp – ''Methanococcus jannaschii''<br /> | ||
**[[2bol]] – Hsp – ''Taenia saginata''<br /> | **[[2bol]] – Hsp – ''Taenia saginata''<br /> | ||
| Line 45: | Line 50: | ||
*Hsp33 | *Hsp33 | ||
| + | **[[3kkl]] – yHsp33 <br /> | ||
**[[1hw7]], [[3m7m]] – EcHsp33 NTD <br /> | **[[1hw7]], [[3m7m]] – EcHsp33 NTD <br /> | ||
**[[1i7f]] – EcHsp33 chaperone domain (mutant)<br /> | **[[1i7f]] – EcHsp33 chaperone domain (mutant)<br /> | ||
| Line 69: | Line 75: | ||
**[[2qld]] – hHsp40 residues 158-340<br /> | **[[2qld]] – hHsp40 residues 158-340<br /> | ||
| - | **[[1hdj]], [[2ctq]], [[6iws]] – hHsp40 J domain 1-76 - NMR<br /> | + | **[[1hdj]], [[2ctq]], [[2lgw]], [[2m6y]], [[6iws]] – hHsp40 J domain 1-76 - NMR<br /> |
| + | **[[6byr]] – hHsp40 J domain 1-70 + CAMP-dependent protein kinase<br /> | ||
**[[6z5n]] – hHsp40 1-110 – NMR<br /> | **[[6z5n]] – hHsp40 1-110 – NMR<br /> | ||
**[[6cgh]] – hHsp40 346-432 – NMR<br /> | **[[6cgh]] – hHsp40 346-432 – NMR<br /> | ||
**[[6u3r]], [[6u3s]] – hHsp40 1-127+CT – NMR<br /> | **[[6u3r]], [[6u3s]] – hHsp40 1-127+CT – NMR<br /> | ||
**[[7jsq]] – hHsp40 CT – NMR<br /> | **[[7jsq]] – hHsp40 CT – NMR<br /> | ||
| + | **[[7ndx]] – hHsp40 CT + NudC peptide<br /> | ||
**[[7ciz]], [[7cj0]] – hHsp40 CT + DNA replication licensing factor + histone H3.4 + histone H4<br /> | **[[7ciz]], [[7cj0]] – hHsp40 CT + DNA replication licensing factor + histone H3.4 + histone H4<br /> | ||
**[[6jmg]] – DnaJ + GTP - frog<br /> | **[[6jmg]] – DnaJ + GTP - frog<br /> | ||
| Line 90: | Line 98: | ||
*Hsp47 | *Hsp47 | ||
| - | **[[3zha]] – dHsp47 + collagen peptide | + | **[[4au4]] – dHsp47 - dog<br /> |
| + | **[[3zha]] – dHsp47 + collagen peptide<br /> | ||
* Hsp60 mitochondrial | * Hsp60 mitochondrial | ||
| - | **[[7azp]] – hHsp60 – Cryo EM<br /> | + | **[[7azp]], [[7l7l]], [[7l7s]] – hHsp60 – Cryo EM<br /> |
| - | **[[4pj1]], [[6ht7]] – hHsp60 + hHsp10<br /> | + | **[[4pj1]], [[6ht7]] – hHsp60 + hHsp10 + ADP<br /> |
**[[6mrc]], [[6mrd]] – hHsp60 + hHsp10 + ADP – Cryo EM<br /> | **[[6mrc]], [[6mrd]] – hHsp60 + hHsp10 + ADP – Cryo EM<br /> | ||
| Line 103: | Line 112: | ||
**[[3iyf]] - MmHsp60 - GroEL – open state<br /> | **[[3iyf]] - MmHsp60 - GroEL – open state<br /> | ||
**[[3e76]] – EcHsp60 – GroEL+Tl ion – ''Escherichia coli''<br /> | **[[3e76]] – EcHsp60 – GroEL+Tl ion – ''Escherichia coli''<br /> | ||
| - | **[[2nwc]], [[1oel]], [[1grl]], [[1la1]] - EcHsp60 – GroEL<br /> | + | **[[2nwc]], [[1oel]], [[1grl]], [[1la1]], [[7v98]] - EcHsp60 – GroEL<br /> |
| - | **[[2eu1]] - EcHsp60 (mutant) – GroEL<br /> | + | **[[2eu1]], [[7v9r]] - EcHsp60 (mutant) – GroEL<br /> |
**[[2cgt]] - EcHsp60 – GroEL+ADP+capsid assembly protein Gp31<br /> | **[[2cgt]] - EcHsp60 – GroEL+ADP+capsid assembly protein Gp31<br /> | ||
**[[2c7c]], [[2c7d]] - EcHsp60 – GroEL+GroES – cryo EM<br /> | **[[2c7c]], [[2c7d]] - EcHsp60 – GroEL+GroES – cryo EM<br /> | ||
| Line 115: | Line 124: | ||
**[[4v4o]] - TtHsp60 – GroEL+GroES <br /> | **[[4v4o]] - TtHsp60 – GroEL+GroES <br /> | ||
**[[1ass]], [[1asx]] - Hsp60 – GroEL apical domain – ''Thermoplasma acidophilum''<br /> | **[[1ass]], [[1asx]] - Hsp60 – GroEL apical domain – ''Thermoplasma acidophilum''<br /> | ||
| + | |||
| + | * Hsp65 | ||
| + | |||
| + | **[[3rtk]] – MtHsp65 – ''Mycobacterium tuberculosis''<br /> | ||
* Hsp70 – 3 domains: N-terminus ATPase hydrolyzes ATP to ADP (NBD) residues 1-380; hydrophobic amino acid binding domain (SBD) residues 381-564: C-terminus lid domain (CT) residues 534-641. | * Hsp70 – 3 domains: N-terminus ATPase hydrolyzes ATP to ADP (NBD) residues 1-380; hydrophobic amino acid binding domain (SBD) residues 381-564: C-terminus lid domain (CT) residues 534-641. | ||
| Line 150: | Line 163: | ||
**[[6s02]] – PfHsp70 NTD+ADP <br /> | **[[6s02]] – PfHsp70 NTD+ADP <br /> | ||
**[[7ooe]], [[7oog]], [[7ooh]], [[7p31]] – PfHsp70 NTD+AMP derivative + inhibitor <br /> | **[[7ooe]], [[7oog]], [[7ooh]], [[7p31]] – PfHsp70 NTD+AMP derivative + inhibitor <br /> | ||
| + | **[[7nqr]], [[7nqs]], [[7nqu]], [[7nqz]] - PfHsp70 NBD + inhibitor<br /> | ||
**[[6zhi]] - PfHsp70 CT + peptide<br /> | **[[6zhi]] - PfHsp70 CT + peptide<br /> | ||
| Line 161: | Line 175: | ||
**[[4b9q]] - EcDnaK NBD + SBD + ATP<br /> | **[[4b9q]] - EcDnaK NBD + SBD + ATP<br /> | ||
| + | **[[7ko2]], [[7krt]], [[7kru]], [[7krv]] - EcDnaK (mutant) + ATP<br /> | ||
**[[5oow]] - EcDnaK + AMPPCP<br /> | **[[5oow]] - EcDnaK + AMPPCP<br /> | ||
**[[5nro]] – EcDnaK (mutant) + DnaJ<br /> | **[[5nro]] – EcDnaK (mutant) + DnaJ<br /> | ||
| Line 172: | Line 187: | ||
**[[1q5l]] - EcDnaK SBD + peptide – NMR<br /> | **[[1q5l]] - EcDnaK SBD + peptide – NMR<br /> | ||
**[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]], [[7jmm]], [[7jn8]], [[7jn9]], [[7jne]], [[7n6j]], [[7n6k]], [[7n6l]], [[7n6m]] – EcDnaK SBD + peptide<br /> | **[[3dpp]], [[3dpq]], [[3dpo]], [[1dky]], [[3qnj]], [[4e81]], [[4ezn]], [[4ezo]], [[4ezp]], [[4ezq]], [[4ezr]], [[4ezs]], [[4ezt]], [[4ezu]], [[4ezv]], [[4ezw]], [[4ezx]], [[4ezy]], [[4ezz]], [[4f00]], [[4hy9]], [[4hyb]], [[4jwc]], [[4jwd]], [[4jwe]], [[4jwi]], [[4r5i]], [[4f01]], [[7jmm]], [[7jn8]], [[7jn9]], [[7jne]], [[7n6j]], [[7n6k]], [[7n6l]], [[7n6m]] – EcDnaK SBD + peptide<br /> | ||
| - | **[[7kzi]], [[7kzu]] – EcDnaK/peptide<br /> | + | **[[7krw]], [[7kzi]], [[7kzu]] – EcDnaK/peptide<br /> |
**[[1q5l]] - EcDnaK SBD +peptide – NMR<br /> | **[[1q5l]] - EcDnaK SBD +peptide – NMR<br /> | ||
**[[4r5g]] - EcDnaK CT + inhibitor<br /> | **[[4r5g]] - EcDnaK CT + inhibitor<br /> | ||
| Line 186: | Line 201: | ||
**[[5f3k]], [[5f5r]] – hHsp75 NTD<br /> | **[[5f3k]], [[5f5r]] – hHsp75 NTD<br /> | ||
| - | **[[5hph]] – hHsp75 residues 60-554<br /> | + | **[[5hph]], [[7ulk]] – hHsp75 residues 60-554<br /> |
**[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]], [[7c7b]], [[7c7c]] – hHsp75 + inhibitor<br /> | **[[4z1f]], [[4z1g]], [[4z1h]], [[4z1i]], [[5y3n]], [[5y3o]], [[7c04]], [[7c05]], [[7c7b]], [[7c7c]] – hHsp75 + inhibitor<br /> | ||
| + | **[[6xg6]] – hHsp75 residues 60-704 + ADP – Cryo EM<br /> | ||
| + | **[[7kck]], [[7klu]], [[7klv]] – hHsp75 residues 60-704 + AMPPNP – Cryo EM<br /> | ||
| + | **[[7kcl]], [[7kcm]] – hHsp75 residues 60-704 + SDHB + AMPPNP – Cryo EM<br /> | ||
*Hsp83 | *Hsp83 | ||
| Line 193: | Line 211: | ||
**[[3u67]] – LmHsp83 NTD + ADP – ''Leishmania major'' | **[[3u67]] – LmHsp83 NTD + ADP – ''Leishmania major'' | ||
| - | * Hsp90 – 4 domains: N-terminus (NTD) residues 1-236; linker; middle (MD); C-terminus (CT) | + | * Hsp90 – 4 domains: N-terminus (NTD) residues 1-236; linker 237-283; middle (MD) 284-543; C-terminus (CT) |
*''Hsp90-α NTD'' | *''Hsp90-α NTD'' | ||
| - | **[[3t0h]], [[5j2v]], [[6gpw]] - hHsp90 NTD – human<br /> | + | **[[3t0h]], [[5j2v]], [[6gpw]], [[7s8y]], [[7s8z]][[5xr]], - hHsp90 NTD – human<br /> |
**[[5j80]], [[6gr4]], [[6gp4]] - hHsp90 NTD (mutant)<br /> | **[[5j80]], [[6gr4]], [[6gp4]] - hHsp90 NTD (mutant)<br /> | ||
**[[2h8m]], [[2hch]], [[2gqp]] – dHsp90B1 NTD <br /> | **[[2h8m]], [[2hch]], [[2gqp]] – dHsp90B1 NTD <br /> | ||
| Line 216: | Line 234: | ||
**[[2k5b]] - hHsp90 NTD+Cdc37 – NMR - docking<br /> | **[[2k5b]] - hHsp90 NTD+Cdc37 – NMR - docking<br /> | ||
**[[3eko]], [[3ekr]] - hHsp90 NTD+dihydroxyphenyl amide<br /> | **[[3eko]], [[3ekr]] - hHsp90 NTD+dihydroxyphenyl amide<br /> | ||
| - | **[[3bm9]], [[3bmy]], [[5xre]], [[5xrb]], [[5xr9]], [[5xr5]], [[5xqe]], [[5xqd]] - hHsp90 NTD+ oxazole derivative<br /> | + | **[[3bm9]], [[3bmy]], [[5xrd]], [[5xre]], [[5xrb]], [[5xr9]], [[5xr5]], [[5xqe]], [[5xqd]] - hHsp90 NTD+ oxazole derivative<br /> |
**[[2of6]], [[3b24]], [[3b27]], [[3b28]], [[3r92]] - hHsp90 NTD+triazine derivative<br /> | **[[2of6]], [[3b24]], [[3b27]], [[3b28]], [[3r92]] - hHsp90 NTD+triazine derivative<br /> | ||
| - | **[[5j20]], [[5j27]], [[5j2x]], [[5j64]], [[5j6l]], [[5j6m]], [[5j82]], [[5j86]], [[5j8m]], [[5j6n]], [[5j8u]], [[5j9x]] - hHsp90-α NTD - hHsp90-a NTD+triazol derivative<br /> | + | **[[5j20]], [[5j27]], [[5j2x]], [[5j64]], [[5j6l]], [[5j6m]], [[5j82]], [[5j86]], [[5j8m]], [[5j6n]], [[5j8u]], [[5j9x]], [[8agi]], [[8agl]] - hHsp90-α NTD +triazol derivative<br /> |
| - | **[[2qfo]], [[3nmq]], [[3r4m]], [[3r4n]], [[3r4o]], [[3r4p]], [[3b25]], [[3b26]], [[2jcc]], [[3rlp]], [[3rlq]], [[3rlr]], [[2wi1]], [[2wi2]], [[2wi3]], [[2wi4]], [[2wi5]], [[2wi6]], [[2wi7]], [[2jjc]], [[5fnc]] - hHsp90 NTD+pyrimidine derivative<br /> | + | **[[8agj]] - hHsp90-a NTD (mutant) +triazol derivative<br /> |
| + | **[[2qfo]], [[3nmq]], [[3r4m]], [[3r4n]], [[3r4o]], [[3r4p]], [[3b25]], [[3b26]], [[2jcc]], [[3rlp]], [[3rlq]], [[3rlr]], [[2wi1]], [[2wi2]], [[2wi3]], [[2wi4]], [[2wi5]], [[2wi6]], [[2wi7]], [[2jjc]], [[5fnc]], [[7dmc]], [[7s98]], [[7s99]], [[7s9f]], [[7s9g]], [[7s9h]], [[7s9i]] - hHsp90 NTD+pyrimidine derivative<br /> | ||
| + | **[[7a90]], [[7s95]] - hHsp90 NTD+ adenine <br /> | ||
**[[6f1n]] - hHsp90 NTD+pyridine derivative<br /> | **[[6f1n]] - hHsp90 NTD+pyridine derivative<br /> | ||
**[[1uy6]], [[1uy7]], [[1uy8]], [[1uy9]], [[1uyc]], [[1uyd]], [[1uye]], [[1uyf]], [[1uyg]], [[1uyh]], [[1uyi]], [[1uyk]], [[1uyl]], [[6el5]], [[2fwy]], [[2fwz]], [[2h55]], [[3o0i]], [[6cyh]], [[6cyg]], [[6b9a]], [[6b99]] - hHsp90 NTD+purine derivative<br /> | **[[1uy6]], [[1uy7]], [[1uy8]], [[1uy9]], [[1uyc]], [[1uyd]], [[1uye]], [[1uyf]], [[1uyg]], [[1uyh]], [[1uyi]], [[1uyk]], [[1uyl]], [[6el5]], [[2fwy]], [[2fwz]], [[2h55]], [[3o0i]], [[6cyh]], [[6cyg]], [[6b9a]], [[6b99]] - hHsp90 NTD+purine derivative<br /> | ||
| Line 253: | Line 273: | ||
**[[6cjr]], [[6cjs]] – CaHsp90 NTD + inhibitor<br /> | **[[6cjr]], [[6cjs]] – CaHsp90 NTD + inhibitor<br /> | ||
**[[7k9s]], [[7k9u]], [[7k9v]], [[7k9w]] – CnHsp90 NTD + inhibitor<br /> | **[[7k9s]], [[7k9u]], [[7k9v]], [[7k9w]] – CnHsp90 NTD + inhibitor<br /> | ||
| + | |||
| + | *''Hsp90-a NTD+linker residues 1-293'' | ||
| + | |||
| + | **[[7ur3]] - hHsp90 + inhibitor <br /> | ||
*''Hsp90-α MD'' | *''Hsp90-α MD'' | ||
| + | **[[6ksq]] - hHsp90 MD <br /> | ||
**[[2gq0]] - EcHsp90 MD<br /> | **[[2gq0]] - EcHsp90 MD<br /> | ||
| Line 269: | Line 294: | ||
*''Hsp90-α MD + CT'' residues 293-732 | *''Hsp90-α MD + CT'' residues 293-732 | ||
| - | **[[3q6m]], [[3q6n]] - hHsp90 MD + CT<br /> | + | **[[3q6m]], [[3q6n]], [[7rxz]], [[7ry0]], [[7ry1]] - hHsp90 MD + CT<br /> |
**[[2o1t]] – dHsp90B1 MD+CT<br /> | **[[2o1t]] – dHsp90B1 MD+CT<br /> | ||
| - | *''Hsp90-α full length'' | + | *''Hsp90-α full length 1-732'' |
| - | **[[6xg6]] - hHsp90 + ADP – Cryo EM <br /> | ||
**[[2qf6]] - hHsp90 + antigen<br /> | **[[2qf6]] - hHsp90 + antigen<br /> | ||
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br /> | **[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br /> | ||
| + | **[[7l7j]] - hHsp90 + P23 + ANP – Cryo EM <br /> | ||
| + | **[[7krj]] - hHsp90 + GR + P23 + ATP – Cryo EM <br /> | ||
| + | **[[8h77]] - hHsp90 + AhR + P23 + XAP2 + ADP – Cryo EM <br /> | ||
| + | **[[7l7i]] - hHsp90 + FKBP51 + P23 + ANP – Cryo EM <br /> | ||
| + | **[[7kw7]] - hHsp90 + Hsp70 + GR + STI1 + ADP – Cryo EM <br /> | ||
**[[2o1u]] – dHsp90B1+AMPPNP<br /> | **[[2o1u]] – dHsp90B1+AMPPNP<br /> | ||
**[[2o1v]] - dHsp90B1+ADP<br /> | **[[2o1v]] - dHsp90B1+ADP<br /> | ||
| Line 284: | Line 313: | ||
*Hsp90-β | *Hsp90-β | ||
| + | **[[8eob]] - hHsp90 – Cryo EM <br /> | ||
**[[6n8w]] - hHsp90 NTD <br /> | **[[6n8w]] - hHsp90 NTD <br /> | ||
**[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br /> | **[[5fwk]], [[5fwl]], [[5fwm]], [[5fwp]] – hHsp90 + CDC37 + CDK4<br /> | ||
| - | **[[1uym]], [[6n8y]] - hHsp90 NTD+ purine inhibitor<br /> | + | **[[1uym]], [[6n8y]], [[7ulj]] - hHsp90 NTD+ purine inhibitor<br /> |
**[[5uc4]], [[5uch]], [[5uci]], [[5ucj]], [[4o04]], [[4o05]], **[[4o07]] - hHsp90-b NTD + inhibitor<br /> | **[[5uc4]], [[5uch]], [[5uci]], [[5ucj]], [[4o04]], [[4o05]], **[[4o07]] - hHsp90-b NTD + inhibitor<br /> | ||
**[[3nmq]] - hHsp90 NTD+pyrimidine derivative | **[[3nmq]] - hHsp90 NTD+pyrimidine derivative | ||
**[[3pry]] – hHsp90 MD<br /> | **[[3pry]] – hHsp90 MD<br /> | ||
| + | **[[7zub]] - hHsp90 + AIP + AH receptor + ADP - Cryo EM <br /> | ||
| + | **[[8e0a]] - hHsp90 + AIPL1 + ANP – Cryo EM <br /> | ||
| + | **[[7z37]], [[7z38]] - hHsp90 + Cdc37 + RAF-1 – Cryo EM <br /> | ||
| + | **[[8gae]] - hHsp90 + Cdc37 + RAF-1 + PP5 – Cryo EM <br /> | ||
| + | **[[7zr0]] - hHsp90 + Cdc37 + BRAF – Cryo EM <br /> | ||
| + | **[[7zr5]], [[7zr6]] - hHsp90 + Cdc37 + BRAF + PP5 – Cryo EM <br /> | ||
| + | **[[7y04]] - mHsp90 + AH receptor + P23 + ADP - mouse - Cryo EM <br /> | ||
* Hsp82 is the yeast equivalent of Hsp90 in mammals | * Hsp82 is the yeast equivalent of Hsp90 in mammals | ||
| Line 331: | Line 368: | ||
**[[1khy]] – EcClpB NTD <br /> | **[[1khy]] – EcClpB NTD <br /> | ||
**[[1jbk]] – EcClpB nucleotide binding domain 1<br /> | **[[1jbk]] – EcClpB nucleotide binding domain 1<br /> | ||
| + | **[[1yg6]] – EcClpP<br /> | ||
| + | **[[1yg8]], [[3hln]] – EcClpP (mutant)<br /> | ||
| + | **[[2fzs]], [[7mk5]] – EcClpP + inhibitor<br /> | ||
| + | **[[6nb1]] – EcClpP + activator<br /> | ||
| + | **[[3mt6]] – EcClpP + Adep1<br /> | ||
| + | **[[6wr2]], [[6wsg]] – EcClpP + ClpX – Cryo EM<br /> | ||
| + | **[[6wrf]] – EcClpP + ClpX + GFP – Cryo EM<br /> | ||
| + | **[[8et3]] – EcClpP + ClpX + GFP + SSPB – Cryo EM<br /> | ||
**[[4iod]], [[4irf]] - PfClpB <br /> | **[[4iod]], [[4irf]] - PfClpB <br /> | ||
**[[1qvr]] - TtClpB <br /> | **[[1qvr]] - TtClpB <br /> | ||
| Line 356: | Line 401: | ||
**[[7m1l]], [[7m1m]] – ClpP2 – ''Pseudomonas aeruginosa''<br /> | **[[7m1l]], [[7m1m]] – ClpP2 – ''Pseudomonas aeruginosa''<br /> | ||
**[[6cfd]] – ClpP + antibiotic – ''Enterococcus faecium''<br /> | **[[6cfd]] – ClpP + antibiotic – ''Enterococcus faecium''<br /> | ||
| + | **[[7tfm]] – ClpP N-domain – ''Leishmania mexicana''<br /> | ||
*Hsp101 | *Hsp101 | ||
| Line 374: | Line 420: | ||
**[[5zui]] – ChtHsp104 – ''Chaetomium thermophilum''<br /> | **[[5zui]] – ChtHsp104 – ''Chaetomium thermophilum''<br /> | ||
**[[7cg3]] – ChtHsp104 - Cryo EM<br /> | **[[7cg3]] – ChtHsp104 - Cryo EM<br /> | ||
| + | **[[5d4w]] – ChtHsp104 (mutant)<br /> | ||
* Hsp110 in mammals is named Sse1, Sse2 in yeast | * Hsp110 in mammals is named Sse1, Sse2 in yeast | ||
| Line 411: | Line 458: | ||
**[[5ycq]] – EcHspQ<br /> | **[[5ycq]] – EcHspQ<br /> | ||
| + | |||
| + | *Hsp DegP or Periplasmic serine endoprotease DegP; Domains PDZ1 38-385; PDZ2 400-474 | ||
| + | |||
| + | **[[3mh4]] – EcDegP <br /> | ||
| + | **[[1ky9]] – EcDegP (mutant) <br /> | ||
| + | **[[8f0a]], [[8f0u]], [[8f1t]], [[8f1u]], [[8f21]] – EcDegP + telomeric repeat-binding factor peptide – Cryo EM<br /> | ||
| + | **[[2zle]], [[4a8d]] – EcDegP + OmpC – Cryo EM<br /> | ||
| + | **[[3cs0]], [[3mh5]], [[3mh6]], [[3mh7]], [[3ou0]], [[6jjk]], [[6jjl]], [[6jjo]] – EcDegP + peptide <br /> | ||
| + | **[[3otp]] – EcDegP + lysozyme <br /> | ||
*'''Heat shock cognate protein (Hsc)''' | *'''Heat shock cognate protein (Hsc)''' | ||
| Line 438: | Line 494: | ||
**[[2v7z]] – rHsc70 NBD + SBD – rat<br /> | **[[2v7z]] – rHsc70 NBD + SBD – rat<br /> | ||
**[[7hsc]], [[1ckr]] - rHsc70 sub - NMR<br /> | **[[7hsc]], [[1ckr]] - rHsc70 sub - NMR<br /> | ||
| - | **[[3cqx]] - Hsc70 NBD+BAG domain regulator protein | + | **[[3cqx]] - Hsc70 NBD+BAG domain regulator protein <br /> |
*''Hsc82'' | *''Hsc82'' | ||
| Line 445: | Line 501: | ||
**[[6xlh]] - yHsc82 MD+co-chaperone AHA1 + ADP + ATPgS<br /> | **[[6xlh]] - yHsc82 MD+co-chaperone AHA1 + ADP + ATPgS<br /> | ||
**[[6xld]], [[6xle]], [[6xlf]] - yHsc82 MD+co-chaperone AHA1 + ANP <br /> | **[[6xld]], [[6xle]], [[6xlf]] - yHsc82 MD+co-chaperone AHA1 + ANP <br /> | ||
| + | **[[6xlb]] - yHsc82 MD+co-chaperone AHA1 + ANP – Cryo EM<br /> | ||
**[[6xlg]] - yHsc82 MD+co-chaperone AHA1 + ATPgS<br /> | **[[6xlg]] - yHsc82 MD+co-chaperone AHA1 + ATPgS<br /> | ||
Current revision
3D Structures of Heat Shock Proteins
Updated on 01-May-2023
