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8i7l
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8i7l is ON HOLD Authors: Li, K., Liu, W., Dong, X. Description: Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel i...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel inhibitor== | |
| - | + | <StructureSection load='8i7l' size='340' side='right'caption='[[8i7l]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8i7l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I7L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OIH:1-[3-[(4-chloranyl-2-fluoranyl-phenyl)carbamoylamino]-4-[cyclohexyl(2-methylpropyl)amino]phenyl]pyrrole-2-carboxylic+acid'>OIH</scene>, <scene name='pdbligand=THJ:THIOSULFATE'>THJ</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i7l OCA], [https://pdbe.org/8i7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i7l RCSB], [https://www.ebi.ac.uk/pdbsum/8i7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i7l ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Dong | + | == Function == |
| + | [https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dong X]] | ||
| + | [[Category: Li K]] | ||
| + | [[Category: Liu W]] | ||
Current revision
Crystal structure of indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with a novel inhibitor
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Categories: Homo sapiens | Large Structures | Dong X | Li K | Liu W
