8g21
From Proteopedia
(Difference between revisions)
m (Protected "8g21" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Reelin C-Terminal Region== |
| - | + | <StructureSection load='8g21' size='340' side='right'caption='[[8g21]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8g21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G21 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g21 OCA], [https://pdbe.org/8g21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g21 RCSB], [https://www.ebi.ac.uk/pdbsum/8g21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g21 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/RELN_HUMAN RELN_HUMAN] Lissencephaly syndrome, Norman-Roberts type;Autosomal dominant epilepsy with auditory features. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RELN_HUMAN RELN_HUMAN] Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chandrahas A]] | ||
Current revision
Reelin C-Terminal Region
| |||||||||||
