8ibh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cep57 C-terminal domain== | |
| - | + | <StructureSection load='8ibh' size='340' side='right'caption='[[8ibh]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ibh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IBH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ibh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ibh OCA], [https://pdbe.org/8ibh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ibh RCSB], [https://www.ebi.ac.uk/pdbsum/8ibh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ibh ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN] Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CEP57_HUMAN CEP57_HUMAN] Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.<ref>PMID:22321063</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen T]] | ||
| + | [[Category: Cheng H-C]] | ||
| + | [[Category: Yeh H-W]] | ||
Current revision
Cep57 C-terminal domain
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