Alcohol dehydrogenase 3D structures
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 58: | Line 58: | ||
**[[1ma0]] - hADH III χ chain + dodecanoic acid + NAD<br /> | **[[1ma0]] - hADH III χ chain + dodecanoic acid + NAD<br /> | ||
**[[3qj5]] - hADH III χ chain + inhibitor + NAD<br /> | **[[3qj5]] - hADH III χ chain + inhibitor + NAD<br /> | ||
| + | **[[8gv3]] - hADH III + inhibitor + NAD – Cryo EM | ||
**[[4dl9]], [[4dlb]] – tADH III + NAD – tomato<br /> | **[[4dl9]], [[4dlb]] – tADH III + NAD – tomato<br /> | ||
**[[4dla]] – tADH III<br /> | **[[4dla]] – tADH III<br /> | ||
| Line 73: | Line 74: | ||
**[[1d1s]], [[1agn]] – hADH IV σ chain + NAD<br /> | **[[1d1s]], [[1agn]] – hADH IV σ chain + NAD<br /> | ||
**[[1d1t]] - hADH IV σ chain (mutant) + NAD<br /> | **[[1d1t]] - hADH IV σ chain (mutant) + NAD<br /> | ||
| - | **[[2jhf]], [[2jhg]], [[1het]], [[1heu]], [[1hf3]], [[1ee2]], [[2oxi]], [[2ohx]], [[6adh]], [[7udd]] - hoADH IV e chain + NAD<br /> | + | **[[2jhf]], [[2jhg]], [[1het]], [[1heu]], [[1hf3]], [[1ee2]], [[2oxi]], [[2ohx]], [[6adh]], [[7udd]], [[8g41]] - hoADH IV e chain + NAD<br /> |
**[[6nbb]] - hoADH IV e chain + NAD – Cryo EM<br /> | **[[6nbb]] - hoADH IV e chain + NAD – Cryo EM<br /> | ||
**[[1adb]], [[1adc]], [[1adf]], [[1adg]], [[7adh]], [[5vn1]] - hoADH IV e chain + NAD derivative<br /> | **[[1adb]], [[1adc]], [[1adf]], [[1adg]], [[7adh]], [[5vn1]] - hoADH IV e chain + NAD derivative<br /> | ||
| Line 80: | Line 81: | ||
*ADH IV ternary complex | *ADH IV ternary complex | ||
| - | **[[ | + | **[[1hld]], [[1mg0]], [[4dwv]], [[4dxh]], [[5kjf]], [[6xt2]], [[7jqa]], [[7k35]], [[7ua6]], [[7uc9]], [[7uca]], [[7ucu]], [[7ude]], [[7udr]], [[7uec]], [[7uee]], [[7uef]], [[7uei]], [[7uej]], [[7uhv]], [[7uhw]], [[7uhx]] - hoADH IV e chain + NAD + alcohol |
| - | **[[ | + | **[[3oq6]], [[1qv6]], [[1qv7]], [[1a71]], [[1axe]], [[1axg]], [[4nfh]], [[4nfs]], [[4ng5]], [[5kje]], [[5kjc]], [[5kj6]], [[5kj1]], [[5kcz]], [[5kcp]], [[5cdt]], [[5cds]], [[5cdg]], [[6o91]], [[6oa7]], [[6owm]], [[6owp]], [[7u9n]], [[7uhw]], [[8e39]], [[8e7u]], [[8g2l]], [[8g4v]] – hoADH IV e chain (mutant) + NAD + alcohol<br /> |
| - | **[[1p1r]], [[1ldy]], [[1lde]] - hoADH IV e chain + NADH + formamide derivative<br /> | + | **[[1p1r]], [[1ldy]], [[1lde]], [[7rm6]], [[8ecs]], [[8ect]], [[8ecu]], [[8ee3]] - hoADH IV e chain + NADH + formamide derivative<br /> |
**[[1n92]] - hoADH IV e chain + NAD + pyrazole derivative<br /> | **[[1n92]] - hoADH IV e chain + NAD + pyrazole derivative<br /> | ||
**[[1bto]], [[3bto]] - hoADH IV e chain + NADH + butylthiolane derivative<br /> | **[[1bto]], [[3bto]] - hoADH IV e chain + NADH + butylthiolane derivative<br /> | ||
| - | **[[1n8k]] - hoADH IV e chain (mutant) + NAD + pyrazole<br /> | + | **[[1n8k]], [[5cdu]], [[8g2x]]] - hoADH IV e chain (mutant) +Zn + NAD + pyrazole<br /> |
| - | **[[ | + | **[[8g2s]] - hoADH IV e chain (mutant) + NAD + capric acid |
**[[5vj5]] - hoADH IV e chain + Zn + phenanthroline<br /> | **[[5vj5]] - hoADH IV e chain + Zn + phenanthroline<br /> | ||
**[[5vjg]] - hoADH IV e chain + Zn + bipyridine<br /> | **[[5vjg]] - hoADH IV e chain + Zn + bipyridine<br /> | ||
| Line 92: | Line 93: | ||
**[[5vl0]] - hoADH IV e chain + Zn + formamide derivative <br /> | **[[5vl0]] - hoADH IV e chain + Zn + formamide derivative <br /> | ||
**[[6cy3]], [[6cxx]] - hoADH IV e chain (mutant) + Zn + dephosphoCoA<br /> | **[[6cy3]], [[6cxx]] - hoADH IV e chain (mutant) + Zn + dephosphoCoA<br /> | ||
| - | **[[ | + | **[[8eix]], [[8eiy]] - hoADH IV e chain (mutant) + Zn + Co + NAD + formamide derivative<br /> |
| + | **[[8eiw]] - hoADH IV e chain + Zn + Co + NAD + formamide derivative<br /> | ||
| + | **[[7utw]] - hoADH IV e chain + Zn + Cd + NAD + formamide derivative<br /> | ||
*ADH | *ADH | ||
| Line 112: | Line 115: | ||
**[[4z6k]] – ADH - ''Moraxella''<br /> | **[[4z6k]] – ADH - ''Moraxella''<br /> | ||
**[[7cyi]] – ADH – ''Artemisia annua''<br /> | **[[7cyi]] – ADH – ''Artemisia annua''<br /> | ||
| + | **[[8ij7]] – BgADH – ''Burkholderia gladioli''<br /> | ||
| + | **[[8ij8]] – BgADH (mutant)<br /> | ||
*ADH binary complex | *ADH binary complex | ||
| Line 131: | Line 136: | ||
**[[6qhe]] – ADH + NAD – ''Arthrobacter''<br /> | **[[6qhe]] – ADH + NAD – ''Arthrobacter''<br /> | ||
**[[6z42]] – ADH + Zn – ''Halomonas elongata''<br /> | **[[6z42]] – ADH + Zn – ''Halomonas elongata''<br /> | ||
| + | **[[8ij6]], [[8ijg]] – BgADH + NADP<br /> | ||
| + | **[[8h2a]] – ADH + NAD – ''Formosa agariphila''<br /> | ||
| + | **[[8h2b]] – ADH + NAD – ''Zobellia galactanivorans''<br /> | ||
| + | **[[8uar]] – RrADH + Zn – ''Rhodococcus ruber''<br /> | ||
*ADH ternary complex | *ADH ternary complex | ||
| Line 153: | Line 162: | ||
**[[6c7l]] – TthADH + monophosphoadenosine diphosphate <br /> | **[[6c7l]] – TthADH + monophosphoadenosine diphosphate <br /> | ||
**[[6c75]] – TthADH + NADP + Fe + monophosphoadenosine diphosphate <br /> | **[[6c75]] – TthADH + NADP + Fe + monophosphoadenosine diphosphate <br /> | ||
| + | **[[8uas]] – RrADH + NAD + Zn <br /> | ||
*NADP-dependent ADH | *NADP-dependent ADH | ||
| Line 158: | Line 168: | ||
**[[4gac]] - mADH<br /> | **[[4gac]] - mADH<br /> | ||
**[[4hfj]] – toADH – tobacco<br /> | **[[4hfj]] – toADH – tobacco<br /> | ||
| - | **[[2nvb]] - TbADH (mutant) – ''Thermoanaerobacter brockii''<br /> | + | **[[2nvb]], [[7xl5]] - TbADH (mutant) – ''Thermoanaerobacter brockii''<br /> |
**[[3ftn]], [[3fpc]], [[3fpl]], [[3fsr]] – ADH chimera<br /> | **[[3ftn]], [[3fpc]], [[3fpl]], [[3fsr]] – ADH chimera<br /> | ||
**[[1y9a]] - EhADH – ''Entamoeba histolytica''<br /> | **[[1y9a]] - EhADH – ''Entamoeba histolytica''<br /> | ||
| Line 180: | Line 190: | ||
**[[5yvr]], [[5yvs]] – bspADH (mutant) + Mn + NADP <br /> | **[[5yvr]], [[5yvs]] – bspADH (mutant) + Mn + NADP <br /> | ||
**[[5z2x]], [[7c3v]] – ADH + NADP – ''Kluyveromyces polyspora''<br /> | **[[5z2x]], [[7c3v]] – ADH + NADP – ''Kluyveromyces polyspora''<br /> | ||
| + | **[[7ymu]] – CgADH – ''Candida glabrata''<br /> | ||
| + | **[[7ymb]] – CgADH + NADP <br /> | ||
*R-specific ADH | *R-specific ADH | ||
| Line 187: | Line 199: | ||
**[[1zjy]], [[1zjz]], [[1zk0]], [[1zk1]] – LbRADH (mutant) + NADH + alcohol<br /> | **[[1zjy]], [[1zjz]], [[1zk0]], [[1zk1]] – LbRADH (mutant) + NADH + alcohol<br /> | ||
**[[1zk4]] - LbRADH (mutant) + NADH + acetophenone<br /> | **[[1zk4]] - LbRADH (mutant) + NADH + acetophenone<br /> | ||
| - | **[[4rf4]] – LkADH + Mg - ''Lactobacillus kefiri''<br /> | + | **[[4rf4]], [[7p36]] – LkADH + Mg - ''Lactobacillus kefiri''<br /> |
| - | **[[4rf5]], [[4rf3]] – LkADH (mutant) + Mg <br /> | + | **[[4rf5]], [[4rf3]], [[7p7y]] – LkADH (mutant) + Mg <br /> |
**[[4rf2]] – LkADH + Mg + NADP<br /> | **[[4rf2]] – LkADH + Mg + NADP<br /> | ||
| Line 207: | Line 219: | ||
**[[6zcw]] - PpQADH II + PQQ + Pr<br /> | **[[6zcw]] - PpQADH II + PQQ + Pr<br /> | ||
**[[1kb0]] - QADH I + PQQ + heme – ''Comamonas testosteroni'' | **[[1kb0]] - QADH I + PQQ + heme – ''Comamonas testosteroni'' | ||
| + | |||
| + | *PQQ-dependent ADH | ||
| + | |||
| + | **[[7wmd]] - DaADH – ''Devosia albogilva''<br /> | ||
| + | **[[7wmk]] - DaADH + PQQ <br /> | ||
*Quinone-dependent ADH | *Quinone-dependent ADH | ||
**[[4cvc]], [[4cvb]] – ADH + Zn + PQQ + propanoate – ''Pseudogluconobacter saccharoketogenes''<br /> | **[[4cvc]], [[4cvb]] – ADH + Zn + PQQ + propanoate – ''Pseudogluconobacter saccharoketogenes''<br /> | ||
| + | **[[8gy2]] – ADH + PQQ + heme + ubiquinone + coenzyme Q10 – ''Gluconobactert oxydans'' - Cryo EM<br /> | ||
*Secondary ADH | *Secondary ADH | ||
| Line 232: | Line 250: | ||
***[[3rqs]] - hSCHAD <BR /> | ***[[3rqs]] - hSCHAD <BR /> | ||
***[[1f14]] - hSCHAD (mutant) | ***[[1f14]] - hSCHAD (mutant) | ||
| + | ***[[7yic]] - SCHAD - ''Leifsonia'' <BR /> | ||
**Short chain HADH binary complex | **Short chain HADH binary complex | ||
Current revision
3D Structures of Alcohol dehydrogenase
Updated on 17-September-2024
