8cis
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8cis is ON HOLD Authors: Bradshaw, W.J., Katis, V.L., Fairhead, M., Bountra, C., von Delft, F., Brennan, P.E. Description: The FERM domain of human...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The FERM domain of human moesin with two bound peptides identified by phage display== |
| + | <StructureSection load='8cis' size='340' side='right'caption='[[8cis]], [[Resolution|resolution]] 1.52Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8cis]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CIS FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cis OCA], [https://pdbe.org/8cis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cis RCSB], [https://www.ebi.ac.uk/pdbsum/8cis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cis ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MOES_HUMAN MOES_HUMAN] Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.<ref>PMID:21549406</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Moesin|Moesin]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Bradshaw | + | [[Category: Homo sapiens]] |
| - | [[Category: Fairhead | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| + | [[Category: Bradshaw WJ]] | ||
| + | [[Category: Brennan PE]] | ||
| + | [[Category: Fairhead M]] | ||
| + | [[Category: Katis VL]] | ||
| + | [[Category: Leisner TM]] | ||
| + | [[Category: Pearce KH]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
The FERM domain of human moesin with two bound peptides identified by phage display
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