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8cks
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8cks is ON HOLD Authors: Dolot, R.M., Kaniowski, D., Ebenryter-Olbinska, K., Szczupak, P., Suwara, J., Nawrot, B.C. Description: Crystal structure ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Human Serum Albumin in complex with FESAN== | |
| - | + | <StructureSection load='8cks' size='340' side='right'caption='[[8cks]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8cks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CKS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UZC:3,3-commo-bis(1,2-dicarba-3-ferra-closo-dodecaborane)'>UZC</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cks OCA], [https://pdbe.org/8cks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cks RCSB], [https://www.ebi.ac.uk/pdbsum/8cks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cks ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dolot RM]] | ||
| + | [[Category: Ebenryter-Olbinska K]] | ||
| + | [[Category: Kaniowski D]] | ||
| + | [[Category: Nawrot BC]] | ||
| + | [[Category: Suwara J]] | ||
| + | [[Category: Szczupak P]] | ||
Current revision
Crystal structure of Human Serum Albumin in complex with FESAN
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