8cks

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8cks" [edit=sysop:move=sysop])
Current revision (11:59, 23 October 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8cks is ON HOLD
+
==Crystal structure of Human Serum Albumin in complex with FESAN==
-
 
+
<StructureSection load='8cks' size='340' side='right'caption='[[8cks]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-
Authors: Dolot, R.M., Kaniowski, D., Ebenryter-Olbinska, K., Szczupak, P., Suwara, J., Nawrot, B.C.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8cks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CKS FirstGlance]. <br>
-
Description: Crystal structure of Human Serum Albumin in complex with FESAN
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Nawrot, B.C]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cks OCA], [https://pdbe.org/8cks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cks RCSB], [https://www.ebi.ac.uk/pdbsum/8cks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cks ProSAT]</span></td></tr>
-
[[Category: Kaniowski, D]]
+
</table>
-
[[Category: Szczupak, P]]
+
== Disease ==
-
[[Category: Suwara, J]]
+
[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
-
[[Category: Dolot, R.M]]
+
== Function ==
-
[[Category: Ebenryter-Olbinska, K]]
+
[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Dolot RM]]
 +
[[Category: Ebenryter-Olbinska K]]
 +
[[Category: Kaniowski D]]
 +
[[Category: Nawrot BC]]
 +
[[Category: Suwara J]]
 +
[[Category: Szczupak P]]

Current revision

Crystal structure of Human Serum Albumin in complex with FESAN

PDB ID 8cks

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools