8g7k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==mtHsp60 V72I apo focus== |
| - | + | <StructureSection load='8g7k' size='340' side='right'caption='[[8g7k]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8g7k]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G7K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g7k OCA], [https://pdbe.org/8g7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g7k RCSB], [https://www.ebi.ac.uk/pdbsum/8g7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g7k ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Autosomal dominant spastic paraplegia type 13;Pelizaeus-Merzbacher-like disease due to HSPD1 mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Braxton JR]] | ||
| + | [[Category: Gestwicki JE]] | ||
| + | [[Category: Shao H]] | ||
| + | [[Category: Southworth DR]] | ||
| + | [[Category: Tse E]] | ||
Current revision
mtHsp60 V72I apo focus
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