4qxz
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4qxz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QXZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4qxz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QXZ FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qxz OCA], [https://pdbe.org/4qxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qxz RCSB], [https://www.ebi.ac.uk/pdbsum/4qxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qxz ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qxz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qxz OCA], [https://pdbe.org/4qxz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qxz RCSB], [https://www.ebi.ac.uk/pdbsum/4qxz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qxz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/A0A0H3JSS7_STAAM A0A0H3JSS7_STAAM] | [https://www.uniprot.org/uniprot/A0A0H3JSS7_STAAM A0A0H3JSS7_STAAM] | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The ywpF gene (SAV2097) of the Staphylococcus aureus strain Mu50 encodes the YwpF protein, which may play a role in antibiotic resistance. Here, we report the first crystal structure of the YwpF superfamily from S. aureus at 2.5-A resolution. The YwpF structure consists of two regions: an N-terminal core beta-barrel domain that shows structural similarity to type VI secretion system (T6SS) proteins (e.g., Hcp1, Hcp3, and EvpC) and a C-terminal two-helix pair. Although the monomer structure of S. aureus YwpF resembles those of T6SS proteins, the dimer/tetramer model of S. aureus YwpF is distinct from the functionally important hexameric ring of T6SS proteins. We therefore suggest that the S. aureus YwpF may have a different function compared to T6SS proteins. | ||
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| - | Crystal structure of YwpF from Staphylococcus aureus reveals its architecture comprised of a beta-barrel core domain resembling type VI secretion system proteins and a two-helix pair.,Lee SJ, Lee KY, Lee KY, Kim DG, Kim SJ, Lee BJ Proteins. 2015 Apr;83(4):781-8. doi: 10.1002/prot.24774. Epub 2015 Feb 28. PMID:25663006<ref>PMID:25663006</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 4qxz" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal structure of a hypothetical protein from Staphylococcus aureus
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