User:Hannah E. Beaven/Sandbox 1

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(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...)
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==Your Heading Here (maybe something like 'Structure')==
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=''Thyroid Stimulating Hormone Receptor (TSHR) Structure and Function''=
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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This is a default text for your page '''Hannah E. Beaven/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
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<StructureSection load='7t9i' size='350' frame='true' side='right' caption='Thyroid Stimulating Hormone Receptor 7t9i' scene='95/954049/P10_spacefill_zoom/1'>
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== Disease ==
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== Introduction ==
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An investigation of the thyroid stimulating hormone receptor (TSHR) structure and function can be found [https://www.biorxiv.org/content/10.1101/2022.01.06.475289v1.full.pdf here] <ref name="Faust">PMID:35940205</ref>.
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== Relevance ==
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== Structure and Function ==
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== Structural highlights ==
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=== Domains ===
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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=== Hinge Region ===
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<scene name='95/954049/P10_spacefill_zoom/2'>Overall TSHR structure with the p10 hinge region highlighted in white spacefill</scene>
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=== Activation ===
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[[Image:p10_intxn.png|400 px|right|thumb|Figure 1]]
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== Relevance ==
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A sentence for placing an example reference <ref name="Ransey">PMID:28504306</ref>. I want to cite the example reference a second time <ref name="Ransey" />.
</StructureSection>
</StructureSection>
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== References ==
== References ==
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<references/>
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<references/>
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== Student Contributors ==

Current revision

Thyroid Stimulating Hormone Receptor (TSHR) Structure and Function

Thyroid Stimulating Hormone Receptor 7t9i

Drag the structure with the mouse to rotate

References

  1. Faust B, Billesbolle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A. Autoantibody mimicry of hormone action at the thyrotropin receptor. Nature. 2022 Aug 8. pii: 10.1038/s41586-022-05159-1. doi:, 10.1038/s41586-022-05159-1. PMID:35940205 doi:http://dx.doi.org/10.1038/s41586-022-05159-1
  2. 2.0 2.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

Proteopedia Page Contributors and Editors (what is this?)

Hannah E. Beaven

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