8cn3

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m (Protected "8cn3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8cn3 is ON HOLD
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==hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1==
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<StructureSection load='8cn3' size='340' side='right'caption='[[8cn3]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
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Authors: Maseko, S., Sogues, A., Volkov, A., Remaut, H., Twizere, J.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8cn3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_T-cell_lymphotrophic_virus_type_1_(strain_ATK) Human T-cell lymphotrophic virus type 1 (strain ATK)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CN3 FirstGlance]. <br>
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Description: hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cn3 OCA], [https://pdbe.org/8cn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cn3 RCSB], [https://www.ebi.ac.uk/pdbsum/8cn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cn3 ProSAT]</span></td></tr>
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[[Category: Volkov, A]]
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</table>
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[[Category: Remaut, H]]
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== Function ==
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[[Category: Maseko, S]]
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[https://www.uniprot.org/uniprot/DLG1_HUMAN DLG1_HUMAN] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.<ref>PMID:10656683</ref> <ref>PMID:12445884</ref> <ref>PMID:14699157</ref> <ref>PMID:15263016</ref> <ref>PMID:19213956</ref> <ref>PMID:20605917</ref>
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[[Category: Twizere, J.C]]
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== References ==
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[[Category: Sogues, A]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Maseko S]]
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[[Category: Remaut H]]
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[[Category: Sogues A]]
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[[Category: Twizere JC]]
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[[Category: Volkov A]]

Current revision

hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1

PDB ID 8cn3

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OCA

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