8gap
From Proteopedia
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(New page: '''Unreleased structure''' The entry 8gap is ON HOLD Authors: Description: Category: Unreleased Structures) |
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- | '''Unreleased structure''' | ||
- | + | ==Structure of LARP7 protein p65-telomerase RNA complex in telomerase== | |
+ | <StructureSection load='8gap' size='340' side='right'caption='[[8gap]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[8gap]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GAP FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gap OCA], [https://pdbe.org/8gap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gap RCSB], [https://www.ebi.ac.uk/pdbsum/8gap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gap ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TERT_TETTS TERT_TETTS] Catalytic component of telomerase, an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:10944124, PubMed:15696174, PubMed:16462747, PubMed:17322903, PubMed:20713447). TERT is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (PubMed:10944124, PubMed:15696174, PubMed:16462747, PubMed:17322903, PubMed:20713447).<ref>PMID:10944124</ref> <ref>PMID:15696174</ref> <ref>PMID:16462747</ref> <ref>PMID:17322903</ref> <ref>PMID:20713447</ref> | ||
- | + | ==See Also== | |
- | + | *[[Telomerase 3D structures|Telomerase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Synthetic construct]] | ||
+ | [[Category: Tetrahymena thermophila]] | ||
+ | [[Category: Eichhorn CD]] | ||
+ | [[Category: Feigon J]] | ||
+ | [[Category: He Y]] | ||
+ | [[Category: Singh M]] | ||
+ | [[Category: Wang Y]] | ||
+ | [[Category: Yang Y]] | ||
+ | [[Category: Zhou ZH]] |
Current revision
Structure of LARP7 protein p65-telomerase RNA complex in telomerase
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