8gdn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of PmHMGR bound to mevalonate, CoA and NAD.== | |
| - | + | <StructureSection load='8gdn' size='340' side='right'caption='[[8gdn]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8gdn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GDN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MEV:(R)-MEVALONATE'>MEV</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gdn OCA], [https://pdbe.org/8gdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gdn RCSB], [https://www.ebi.ac.uk/pdbsum/8gdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gdn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas mevalonii]] | ||
| + | [[Category: Purohit V]] | ||
| + | [[Category: Stauffacher CV]] | ||
| + | [[Category: Steussy CN]] | ||
Current revision
Structure of PmHMGR bound to mevalonate, CoA and NAD.
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