8ght
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-electron microscopy structure of the zinc transporter from Bordetella bronchiseptica== | |
| - | + | <StructureSection load='8ght' size='340' side='right'caption='[[8ght]], [[Resolution|resolution]] 3.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ght]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bordetella_bronchiseptica Bordetella bronchiseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GHT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ght OCA], [https://pdbe.org/8ght PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ght RCSB], [https://www.ebi.ac.uk/pdbsum/8ght PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ght ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZIP_BORBR ZIP_BORBR] Selective electrodiffusional channel that mediates the uptake of Zn(2+). Exploits in vivo zinc concentration gradients (maintained by cellular zinc homeostasis) to passively move zinc ions into the cytoplasm. ZIPB-mediated zinc flux is dependent upon pH, but independent of the proton motive force. Is also able to import Cd(2+), but is not permeable to Co(2+), Cu(2+), Fe(2+), Mn(2+) and Ni(2+).<ref>PMID:20876577</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bordetella bronchiseptica]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chai J]] | ||
| + | [[Category: Liu Q]] | ||
| + | [[Category: Pang CX]] | ||
| + | [[Category: Shanklin J]] | ||
Current revision
Cryo-electron microscopy structure of the zinc transporter from Bordetella bronchiseptica
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