8of4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8of4 is ON HOLD Authors: Smirnova, E., Bignon, E., Schultz, P., Papai, G., Ben-Shem, A. Description: Nucleosome Bound human SIRT6 (Composite) [[Cat...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Nucleosome Bound human SIRT6 (Composite)== | |
| - | + | <StructureSection load='8of4' size='340' side='right'caption='[[8of4]], [[Resolution|resolution]] 2.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8of4]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OF4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.94Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8of4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8of4 OCA], [https://pdbe.org/8of4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8of4 RCSB], [https://www.ebi.ac.uk/pdbsum/8of4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8of4 ProSAT]</span></td></tr> |
| - | [[Category: Ben-Shem | + | </table> |
| - | [[Category: Bignon | + | == Function == |
| - | [[Category: Papai | + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| - | [[Category: Schultz | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Ben-Shem A]] | ||
| + | [[Category: Bignon E]] | ||
| + | [[Category: Papai G]] | ||
| + | [[Category: Schultz P]] | ||
| + | [[Category: Smirnova E]] | ||
Current revision
Nucleosome Bound human SIRT6 (Composite)
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