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8ofa
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)== | |
| - | + | <StructureSection load='8ofa' size='340' side='right'caption='[[8ofa]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ofa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OFA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=TQ8:N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]-4-METHYL-BENZENESULFONAMIDE'>TQ8</scene>, <scene name='pdbligand=VLF:4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide'>VLF</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ofa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ofa OCA], [https://pdbe.org/8ofa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ofa RCSB], [https://www.ebi.ac.uk/pdbsum/8ofa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ofa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chapman HN]] | ||
| + | [[Category: Ewert W]] | ||
| + | [[Category: Falke S]] | ||
| + | [[Category: Guenther S]] | ||
| + | [[Category: Hinrichs W]] | ||
| + | [[Category: Karnicar K]] | ||
| + | [[Category: Lieske J]] | ||
| + | [[Category: Lindic N]] | ||
| + | [[Category: Loboda J]] | ||
| + | [[Category: Meents A]] | ||
| + | [[Category: Reinke PYA]] | ||
| + | [[Category: Sekirnik A]] | ||
| + | [[Category: Turk D]] | ||
| + | [[Category: Usenik A]] | ||
Current revision
Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)
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Categories: Homo sapiens | Large Structures | Chapman HN | Ewert W | Falke S | Guenther S | Hinrichs W | Karnicar K | Lieske J | Lindic N | Loboda J | Meents A | Reinke PYA | Sekirnik A | Turk D | Usenik A
