8iru

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m (Protected "8iru" [edit=sysop:move=sysop])
Current revision (07:27, 21 November 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8iru is ON HOLD
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==Dopamine Receptor D4R-Gi-Rotigotine complex==
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<StructureSection load='8iru' size='340' side='right'caption='[[8iru]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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Authors: Xu, P., Huang, S., Zhuang, Y., Mao, C., Zhang, Y., Wang, Y., Li, H., Jiang, Y., Zhang, Y., Xu, H.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8iru]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IRU FirstGlance]. <br>
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Description: Dopamine Receptor D4R-Gi-Rotigotine complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=R5F:(6~{S})-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol'>R5F</scene></td></tr>
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[[Category: Zhang, Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iru OCA], [https://pdbe.org/8iru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iru RCSB], [https://www.ebi.ac.uk/pdbsum/8iru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iru ProSAT]</span></td></tr>
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[[Category: Huang, S]]
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</table>
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[[Category: Xu, H.E]]
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== Function ==
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[[Category: Li, H]]
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[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
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[[Category: Zhuang, Y]]
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== References ==
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[[Category: Xu, P]]
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<references/>
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[[Category: Jiang, Y]]
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__TOC__
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[[Category: Wang, Y]]
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</StructureSection>
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[[Category: Mao, C]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Huang S]]
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[[Category: Jiang Y]]
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[[Category: Li H]]
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[[Category: Mao C]]
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[[Category: Wang Y]]
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[[Category: Xu HE]]
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[[Category: Xu P]]
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[[Category: Zhang Y]]
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[[Category: Zhuang Y]]

Current revision

Dopamine Receptor D4R-Gi-Rotigotine complex

PDB ID 8iru

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OCA

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