8iue

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(New page: '''Unreleased structure''' The entry 8iue is ON HOLD Authors: Hou, H., Jin, Q., Ren, Y., Wang, Q., Xu, Y. Description: human RNA polymerase III pre-initiation complex closed DNA 1 [[Ca...)
Current revision (07:40, 3 July 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8iue is ON HOLD
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==RNA polymerase III pre-initiation complex melting complex 1==
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<StructureSection load='8iue' size='340' side='right'caption='[[8iue]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8iue]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IUE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iue OCA], [https://pdbe.org/8iue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iue RCSB], [https://www.ebi.ac.uk/pdbsum/8iue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iue ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/RPAC1_HUMAN RPAC1_HUMAN] Hypomyelination-hypogonadotropic hypogonadism-hypodontia syndrome;Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/RPAC1_HUMAN RPAC1_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft.[UniProtKB:P07703]<ref>PMID:20413673</ref> <ref>PMID:34671025</ref> <ref>PMID:34887565</ref> <ref>PMID:36271492</ref> <ref>PMID:26151409</ref>
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Authors: Hou, H., Jin, Q., Ren, Y., Wang, Q., Xu, Y.
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==See Also==
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*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
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Description: human RNA polymerase III pre-initiation complex closed DNA 1
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Wang, Q]]
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__TOC__
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[[Category: Hou, H]]
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</StructureSection>
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[[Category: Ren, Y]]
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[[Category: Homo sapiens]]
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[[Category: Jin, Q]]
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[[Category: Large Structures]]
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[[Category: Xu, Y]]
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[[Category: Hou H]]
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[[Category: Jin Q]]
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[[Category: Ren Y]]
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[[Category: Wang Q]]
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[[Category: Xu Y]]

Current revision

RNA polymerase III pre-initiation complex melting complex 1

PDB ID 8iue

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