8cn1

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'''Unreleased structure'''
 
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The entry 8cn1 is ON HOLD until Paper Publication
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==hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1==
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<StructureSection load='8cn1' size='340' side='right'caption='[[8cn1]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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Authors: Maseko, S., Sogues, A., Volkov, A., Remaut, H., Twizere, J.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8cn1]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_T-cell_leukemia_virus_type_I Human T-cell leukemia virus type I]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CN1 FirstGlance]. <br>
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Description: hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Volkov, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cn1 OCA], [https://pdbe.org/8cn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cn1 RCSB], [https://www.ebi.ac.uk/pdbsum/8cn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cn1 ProSAT]</span></td></tr>
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[[Category: Remaut, H]]
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</table>
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[[Category: Maseko, S]]
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== Function ==
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[[Category: Twizere, J.C]]
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[https://www.uniprot.org/uniprot/DLG1_HUMAN DLG1_HUMAN] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.<ref>PMID:10656683</ref> <ref>PMID:12445884</ref> <ref>PMID:14699157</ref> <ref>PMID:15263016</ref> <ref>PMID:19213956</ref> <ref>PMID:20605917</ref>
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[[Category: Sogues, A]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human T-cell leukemia virus type I]]
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[[Category: Large Structures]]
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[[Category: Maseko S]]
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[[Category: Remaut H]]
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[[Category: Sogues A]]
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[[Category: Twizere JC]]
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[[Category: Volkov A]]

Current revision

hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1

PDB ID 8cn1

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OCA

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