This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8iy9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8iy9 is ON HOLD Authors: Yadav, M.K., Sarma, P., Chami, M., Banerjee, R., Shukla, A.K. Description: Structure of GPR109A-G protein in complex with ...) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Niacin-GPR109A-G protein complex== | |
| - | + | <StructureSection load='8iy9' size='340' side='right'caption='[[8iy9]], [[Resolution|resolution]] 3.37Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8iy9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IY9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.37Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iy9 OCA], [https://pdbe.org/8iy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iy9 RCSB], [https://www.ebi.ac.uk/pdbsum/8iy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iy9 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Sarma | + | [https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/GNAO_HUMAN GNAO_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Banerjee R]] | ||
| + | [[Category: Chami M]] | ||
| + | [[Category: Sarma P]] | ||
| + | [[Category: Shukla AK]] | ||
| + | [[Category: Yadav MK]] | ||
Current revision
Structure of Niacin-GPR109A-G protein complex
| |||||||||||
Categories: Homo sapiens | Large Structures | Mus musculus | Banerjee R | Chami M | Sarma P | Shukla AK | Yadav MK
