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4x3r

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Current revision (10:46, 10 January 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4x3r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X3R FirstGlance]. <br>
<table><tr><td colspan='2'>[[4x3r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X3R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=686:N-({(1S)-5-[(4-BROMOBENZYL)({6-[4-(4-{4-[4-CARBOXY-3-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)BENZOYL]PIPERAZIN-1-YL}PHENYL)PIPERAZIN-1-YL]PYRIDIN-3-YL}CARBONYL)AMINO]-1-CARBOXYPENTYL}CARBAMOYL)-L-GLUTAMIC+ACID'>686</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=686:N-({(1S)-5-[(4-BROMOBENZYL)({6-[4-(4-{4-[4-CARBOXY-3-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)BENZOYL]PIPERAZIN-1-YL}PHENYL)PIPERAZIN-1-YL]PYRIDIN-3-YL}CARBONYL)AMINO]-1-CARBOXYPENTYL}CARBAMOYL)-L-GLUTAMIC+ACID'>686</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3r OCA], [https://pdbe.org/4x3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x3r RCSB], [https://www.ebi.ac.uk/pdbsum/4x3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x3r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x3r OCA], [https://pdbe.org/4x3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x3r RCSB], [https://www.ebi.ac.uk/pdbsum/4x3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x3r ProSAT]</span></td></tr>
</table>
</table>

Current revision

Avi-GCPII structure in complex with FITC-conjugated GCPII-specific inhibitor

PDB ID 4x3r

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