Efavirenz/emtricitabine/tenofovir

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(New page: <StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/960003/Cv/1'> This is a default text for your page '''Efavirenz/emtricitabine/tenofovir'''....)
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/960003/Cv/1'>
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<StructureSection load='' size='340' side='right' caption='Efavirenz/emtricitabinne/tenofovir' scene='96/960003/Cv/1'>
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This is a default text for your page '''Efavirenz/emtricitabine/tenofovir'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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Efavirenz/emtricitabine/tenofovir, sold under the brand name Atripla among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. It contains [[efavirenz]], [[emtricitabine]], and [[Tenofovir|tenofovir disoproxil]]. It can be used by itself or together with other antiretroviral medications. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) of HIV-1. Tenofovir is a nucleotide reverse transcriptase inhibitor of HIV-1, and it can be classified as an NtRTI. These three drugs work in combination to target the HIV reverse transcriptase protein in three ways, which reduces the virus's capacity to mutate.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
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<scene name='95/958584/Cv/3'>Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz</scene> ([[7kjw]]).
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== Disease ==
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<scene name='95/958584/Cv/4'>Efavirenz binding site</scene>.
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== Relevance ==
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<scene name='95/959998/Cv/4'>Emtricitabine binding site</scene> at reverse transcriptase ([[2no6]]). Water molecules are shown as red spheres.
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== Structural highlights ==
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<scene name='96/960003/Cv/3'>Tenofovir diphosphate (TNV) binding site</scene> at reverse transcriptase ([[3fkb]]). Water molecules are shown as red spheres.
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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<scene name='96/960003/Tnmbindingsite/5'>Tenofovir-monophosphate (TNM) binding site</scene> at reverse transcriptase ([[3fkb]]).
</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

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Efavirenz/emtricitabinne/tenofovir

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

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