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8ixv

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'''Unreleased structure'''
 
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The entry 8ixv is ON HOLD until Paper Publication
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==Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP==
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<StructureSection load='8ixv' size='340' side='right'caption='[[8ixv]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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Authors: Yang, Y.Y., Yi, S.M., Huang, J.W., Chen, C.C., Guo, R.T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ixv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IXV FirstGlance]. <br>
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Description: Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=RZO:[bis(chloranyl)-[[(E)-3-methyl-4-oxidanyl-but-2-enoxy]-oxidanyl-phosphoryl]methyl]phosphonic+acid'>RZO</scene></td></tr>
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[[Category: Huang, J.W]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ixv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ixv OCA], [https://pdbe.org/8ixv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ixv RCSB], [https://www.ebi.ac.uk/pdbsum/8ixv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ixv ProSAT]</span></td></tr>
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[[Category: Yi, S.M]]
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</table>
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[[Category: Chen, C.C]]
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== Function ==
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[[Category: Guo, R.T]]
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[https://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
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[[Category: Yang, Y.Y]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen CC]]
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[[Category: Guo RT]]
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[[Category: Huang JW]]
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[[Category: Yang YY]]
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[[Category: Yi SM]]

Current revision

Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP

PDB ID 8ixv

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