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8j3v
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8j3v is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the transmembrane domain of human PD-L2== | |
| - | + | <StructureSection load='8j3v' size='340' side='right'caption='[[8j3v]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8j3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J3V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j3v OCA], [https://pdbe.org/8j3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j3v RCSB], [https://www.ebi.ac.uk/pdbsum/8j3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j3v ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PD1L2_HUMAN PD1L2_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: OuYang B]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Structure of the transmembrane domain of human PD-L2
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