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7g12
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7g12 is ON HOLD Authors: Ehler, A., Benz, J., Obst, U., Kuhne, H., Rudolph, M.G. Description: Crystal Structure of human FABP4 binding site mutated...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-propan-2-yl-3-(1H-tetrazol-5-yl)pyridin-2-amine== | |
| - | + | <StructureSection load='7g12' size='340' side='right'caption='[[7g12]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7g12]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G12 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=WER:(3M,6P)-N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-(propan-2-yl)-3-(1H-tetrazol-5-yl)pyridin-2-amine'>WER</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g12 OCA], [https://pdbe.org/7g12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g12 RCSB], [https://www.ebi.ac.uk/pdbsum/7g12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g12 ProSAT]</span></td></tr> |
| - | [[Category: Benz | + | </table> |
| - | [[Category: Kuhne | + | == Function == |
| - | [[Category: Obst | + | [https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). |
| - | [[Category: Rudolph | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Benz J]] | ||
| + | [[Category: Ehler A]] | ||
| + | [[Category: Kuhne H]] | ||
| + | [[Category: Obst U]] | ||
| + | [[Category: Rudolph MG]] | ||
Current revision
Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with N-methyl-6-(3-methylthiophen-2-yl)-4-phenyl-N-propan-2-yl-3-(1H-tetrazol-5-yl)pyridin-2-amine
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Categories: Homo sapiens | Large Structures | Benz J | Ehler A | Kuhne H | Obst U | Rudolph MG
