8sxn
From Proteopedia
(Difference between revisions)
m (Protected "8sxn" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of NLRP3 and NEK7 complex== | |
| - | + | <StructureSection load='8sxn' size='340' side='right'caption='[[8sxn]], [[Resolution|resolution]] 4.04Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8sxn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SXN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.04Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YN:1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea'>7YN</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sxn OCA], [https://pdbe.org/8sxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sxn RCSB], [https://www.ebi.ac.uk/pdbsum/8sxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sxn ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/NEK7_HUMAN NEK7_HUMAN] Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1.<ref>PMID:17101132</ref> <ref>PMID:17586473</ref> <ref>PMID:19414596</ref> |
| - | [[Category: Lindahl | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Pietrak | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bottelbergs A]] |
| - | [[Category: Sharma | + | [[Category: Grauwen K]] |
| - | [[Category: | + | [[Category: Haloi N]] |
| - | [[Category: | + | [[Category: Lindahl E]] |
| - | [[Category: | + | [[Category: Matico RE]] |
| - | [[Category: | + | [[Category: Miller R]] |
| + | [[Category: Oehlrich D]] | ||
| + | [[Category: Opdenbosch NV]] | ||
| + | [[Category: Perez-Benito L]] | ||
| + | [[Category: Pietrak B]] | ||
| + | [[Category: Schoubroeck BV]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Suarez J]] | ||
| + | [[Category: Tresadern GJ]] | ||
| + | [[Category: Yin Y]] | ||
| + | [[Category: Yu X]] | ||
Current revision
Structure of NLRP3 and NEK7 complex
| |||||||||||
Categories: Homo sapiens | Large Structures | Bottelbergs A | Grauwen K | Haloi N | Lindahl E | Matico RE | Miller R | Oehlrich D | Opdenbosch NV | Perez-Benito L | Pietrak B | Schoubroeck BV | Sharma S | Suarez J | Tresadern GJ | Yin Y | Yu X
