Kinesin 3D Structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:12, 23 October 2025) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 3: Line 3:
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
 +
 +
*KIF1 heavy chain
 +
 +
**[[5lt0]], [[5lt1]], [[5lt2]], [[5lt3]], [[5lt4]], [[9l6k]], [[9l78]] – hKHC (mutant) - human<br />
 +
**[[7rik]] – hKHC - NMR<br />
 +
**[[1mkj, [[5lt0]]]] – hKHC + ADP<br />
 +
**[[9l7e]] – hKHC (mutant) + ADP<br />
 +
**[[1bg2]] – hKHC MD <br />
 +
**[[3j8x]], [[3j8y]] – hKHC MD + GTP + GDP + tubulin<br />
 +
**[[6ojq]] – hKHC MD + Tubulin + G2P + GTP – Cryo EM<br />
 +
**[[4lnu]] – hKHC + Tubulin + designed ankyrin repeat
 +
**[[4hna]] – hKHC + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4<br />
 +
**[[9l7m]] – hKHC MD + GTP + tubulin – Cryo EM<br />
 +
**[[8ixb]], [[8ixd]], [[8ixe]] – hKHC MD + Tubulin + GMPCPP – Cryo EM<br />
 +
**[[8rhb]], [[8rhh]] – hKHC + Tubulin + AMPPNP – Cryo EM<br />
 +
**[[8rik]], [[8riz]], [[9gnq]] – hKHC + Tubulin + ADP + GDP + GTP – Cryo EM<br />
 +
**[[6ign]], [[6igv]] – mKHC coiled coil domain 444-566 <br />
 +
**[[4atx]] - rKHC MD+ Tubulin – rat - Cryo EM<br />
*KIF1A, KIF1B, KIF1C or kinesin-3
*KIF1A, KIF1B, KIF1C or kinesin-3
-
**[[4ejq]], [[4egx]] - hKIF1A CC1-FHA domain 430-607 - human<br />
 
-
**[[1bg2]] – hKIF MD<br />
 
-
**[[5lt3]], [[5lt4]], [[5lt2]], [[5lt0]], [[5lt1]] – hKIF1 MD (mutant) <br />
 
-
**[[2g1l]] - hKIF1C FHA domain<br />
 
-
**[[5wdh]] – hKIF1C MD<br />
 
-
**[[2eh0]] - hKIF1B FHA domain – NMR<br />
 
-
**[[4hna]], [[4lnu]] – hKIF1 + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4<br />
 
**[[4uxy]] – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM<br />
**[[4uxy]] – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM<br />
-
**[[6ojq]] – hKIF1 MD + Tubulin + G2P + GTP – Cryo EM<br />
 
**[[4uy0]] – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM<br />
**[[4uy0]] – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxt]] - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM <br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxt]] - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM <br />
**[[2p4n]] – hKIF+ Tubulin – EM docking<br />
**[[2p4n]] – hKIF+ Tubulin – EM docking<br />
-
**[[1mkj]] – hKIF MD+docked FNL<br />
 
**[[6zph]] – hKIF MD + KIF-binding protein – Cryo EM<br />
**[[6zph]] – hKIF MD + KIF-binding protein – Cryo EM<br />
 +
**[[9ko8]] – hKIF1C 714-809 + Hook3 553-624 <br />
**[[2wbe]] – bKIF MD+FNL+Tubulin +AMPPNP – bovine <br />
**[[2wbe]] – bKIF MD+FNL+Tubulin +AMPPNP – bovine <br />
**[[3edl]] – bKIF MD+ Tubulin – EM<br />
**[[3edl]] – bKIF MD+ Tubulin – EM<br />
-
**[[3uyq]] – pKIF1A head+AMPPNP – pig<br />
+
**[[8tt7]] - rKIF neck 325-376 - NMR<br />
-
**[[2hxh]] - pKIF1A head+ADP<br />
+
-
**[[2hxf]] - pKIF1A head+AMPPNP<br />
+
-
**[[1ia0]] – pKIF1A MD+Tubulin +ATP <br />
+
-
**[[2zfi]], [[2zfj]], [[2zfk]], [[2zfl]], [[2zfm]] – mKIF1A – mouse<br />
+
-
**[[1vfv]], [[1vfw]] – mKIF1A MD+Mg-AMPPNP<br />
+
-
**[[1vfx]] - mKIF1A MD+ADP-Mg-AlFx<br />
+
-
**[[7eo9]], [[7eob]] - mKIF1A MD (mutant) +ADP-Mg-AlFx<br />
+
-
**[[1vfz]] - mKIF1A MD+ADP-Mg-VO4<br />
+
-
**[[4atx]] - rKIF MD+ Tubulin – rat - Cryo EM<br />
+
-
**[[2owm]] – NcKIF1C MD – ''Neurospora crassa''<br />
+
-
*KIF2A, KIF2B, KIF2C or kinesin-13
+
*KIF-like 1A, KIF-like 1B, KIF-like 1C
-
**[[2heh]], [[4ubf]], [[5y05]] – hKIF2C<br />
+
**[[4ejq]], [[4egx]] – hKIFL 1A CC1-FHA domain 430-607<br />
-
**[[2gry]] – hKIF2+ADP<br />
+
**[[8uts]] – hKIFL 1A MD + tubulin – Cryo EM <br />
-
**[[6bbn]] – hKIF2A MD + Tubulin + Darpin<br />
+
**[[8utn]], [[8uto]], [[8utp]], [[8utq]], [[8uty]] – hKIFL 1A MD + tubulin + ANP + GDP + GTP – Cryo EM <br />
-
**[[5mio]] – hKIF2C MD + Tubulin <br />
+
**[[8utr]] – hKIFL 1A MD + tubulin + ADP – Cryo EM <br />
-
**[[1v8j]], [[5xja]], [[5xjb]] – mKIF2C MD+Mg-ADP<br />
+
**[[8utv]] – hKIFL 1A MD (mutant) + tubulin + ADP – Cryo EM <br />
-
**[[1i5s]] - mKIF2C MD (mutant)+Mg-ADP<br />
+
**[[8utt]], [[8utu]], [[8utw]] – hKIFL 1A MD (mutant) + tubulin + ANP + GDP + GTP – Cryo EM <br />
-
**[[1i6i]] - mKIF2C MD (mutant)+Mg-AMPPCP<br />
+
**[[2g1l]] – hKIFL 1C FHA domain<br />
-
**[[1v8k]] - mKIF2C MD+Mg-AMPPNP<br />
+
**[[5wdh]] – hKIFL 1C MD<br />
 +
**[[2eh0]] – hKIFL 1B FHA domain – NMR<br />
 +
**[[2hxh]] – pKIFL 1A head+ADP - pig<br />
 +
**[[2hxf]] – pKIFL 1A head+AMPPNP<br />
 +
**[[1ia0]] – pKIFL 1A MD+Tubulin +ATP <br />
 +
**[[2zfi]], [[2zfj]], [[2zfk]], [[2zfl]], [[2zfm]] – mKIFL 1A – mouse<br />
 +
**[[1vfv]], [[1vfw]] – mKIFL 1A MD+Mg-AMPPNP<br />
 +
**[[1vfx]] – mKIFL 1A MD+ADP-Mg-AlFx<br />
 +
**[[7eo9]], [[7eob]] – mKIFL 1A MD (mutant) +ADP-Mg-AlFx<br />
 +
**[[1vfz]] – mKIFL 1A MD+ADP-Mg-VO4<br />
 +
**[[2owm]] – NcKIFL 1C MD – ''Neurospora crassa''<br />
 +
 
 +
 
 +
*KIF-like 2A, KIF-like 2C or kinesin-13
 +
 
 +
**[[2heh]], [[4ubf]] – hKIFL 2C<br />
 +
**[[2gry]] – hKIFL 2+ADP<br />
 +
**[[6bbn]] – hKIFL 2A MD + Tubulin + Darpin<br />
 +
**[[9j20]], [[9jwv]] – hKIFL 2A MD + WDR5<br />
 +
**[[5mio]] – hKIFL 2C MD + Tubulin <br />
 +
**[[1v8j]], [[5xja]], [[5xjb]] – mKIFL 2C MD+Mg-ADP<br />
 +
**[[1i5s]] – mKIFL 2C MD (mutant)+Mg-ADP<br />
 +
**[[1i6i]] – mKIFL 2C MD (mutant)+Mg-AMPPCP<br />
 +
**[[1v8k]] – mKIFL 2C MD+Mg-AMPPNP<br />
**[[2vvg]] – KIF2 MD – ''Giardia intestinalis''<br />
**[[2vvg]] – KIF2 MD – ''Giardia intestinalis''<br />
-
*KIF3A, KIF3B, KIF3C or kinesin-2
+
*KIF-like 3A, KIF-like 3B
 +
 
 +
**[[9w9i]] – hKIFL 3A + hKIFL 3B + KAP3 + mAPC – Cryo EM<br />
 +
**[[9w9h]] – hKIFL 3A + hKIFL 3B + KAP3 – Cryo EM<br />
 +
 
 +
*KIF-like 3B, KIF-like 3C or kinesin-2
-
**[[3b6u]], [[3b6v]] – hKIF3B MD<br />
+
**[[3b6u]], [[3b6v]] – hKIFL 3B MD<br />
-
**[[5wde]] – hKIFC3+ADP<br />
+
**[[5wde]] – hKIFL 3C+ADP<br />
*KIF4A, KIF4B or kinesin-4
*KIF4A, KIF4B or kinesin-4
Line 57: Line 85:
*KIF5B, KIF5C or kinesin-1
*KIF5B, KIF5C or kinesin-1
-
**[[6ign]], [[6igv]] – mKIF5B coiled coil domain 444-566 <br />
 
**[[3wrd]] – mKIF5C<br />
**[[3wrd]] – mKIF5C<br />
**[[3x2t]] – mKIF5C + ADP<br />
**[[3x2t]] – mKIF5C + ADP<br />
**[[3j6h]] – mKIF5C MD+Mg-GTP + G2P + tubulin <br />
**[[3j6h]] – mKIF5C MD+Mg-GTP + G2P + tubulin <br />
-
**[[3j8x]], [[3j8y]] – mKIF5C MD+ GTP + GDP + tubulin<br />
+
**[[3j8x]], [[3j8y]] – hKIF5C MD+ GTP + GDP + tubulin<br />
 +
**[[2y5w]], [[2y65]] - DmKIF MD – Drosophila melanogasgter<br />
 +
**[[4pxt]], [[4pxu]] – DmKIF MD (mutant)<br />
 +
**[[1n6m]] – DmKIF MD+FNL<br />
 +
**[[3l1c]] – DmNCD (mutant)<br />
 +
 
 +
*KIF-like 6
 +
 
 +
**[[7wrg]] - CeKIFL - Caenorhabditis elegans<br />
 +
 
 +
*KIF-like 7 or kinesin-4
 +
 
 +
**[[4a14]] – hKIFL 7 MD <br />
 +
**[[2xt3]] – hKIFL 7 MD (mutant)<br />
 +
**[[6mlr]] – hKIFL 7 MD + Tubulin + GTP + GDP + ANP – Cryo EM<br />
 +
**[[6mlq]] – hKIFL 7 MD + Tubulin + GTP + GDP + ADP – Cryo EM<br />
 +
**[[7rx0]] – hKIFL 7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM<br />
 +
 
 +
*KIF8B
 +
 
 +
**[[7z2a]], [[7z2b]], [[7z2c]] – KIF8B + pTUBA+pTUBB +G2P + GTP – Plasmodium berghei – Cryo EM <br />
 +
 
 +
*KIF-like 8
 +
 
 +
**[[9crw]] – hKIFL 8 474-705 <br />
-
*KIF7 or kinesin-4
+
*KIF-like 9 or kinesin-9
-
**[[4a14]] – hKIF7 MD <br />
+
**[[3nwn]] – hKIFL 9+ADP<br />
-
**[[2xt3]] – hKIF7 MD (mutant)<br />
+
-
**[[6mlr]] – hKIF7 MD + Tubulin + GTP + GDP + ANP – Cryo EM<br />
+
-
**[[6mlq]] – hKIF7 MD + Tubulin + GTP + GDP + ADP – Cryo EM<br />
+
-
**[[7rx0]] – hKIF7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM<br />
+
-
*KIF9 or kinesin-9
+
*KIF-like 10A or kinesin-6
-
**[[3nwn]] – hKIF9+ADP<br />
+
**[[3j2u]] – hKIFL 10A head domain – Cryo EM<br />
 +
**[[6b0c]], [[6b0l]] – DmKIFL 10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
 +
**[[6vpp]] – DmKIFL 61F + tubulin + GTP + GDP + Mg – Cryo EM<br />
 +
**[[6vpo]] – DmKIFL 61F + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
 +
**[[6b0i]] – DmKIFL 10A + tubulin + GTP + GDP + Mg – Cryo EM<br />
-
*KIF10A or kinesin-6
+
*KIF-like 11 or kinesin-5 or Eg5
-
**[[3j2u]] – hKIF10A head domain – Cryo EM<br />
+
**[[4b7b]] – hKIFL 11 (mutant) + ADP + Co + Cd <br />
-
**[[6b0c]], [[6b0l]] – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
+
**[[3ken]], [[2wog]], [[2x2r]], [[2xae]], [[4bbg]] – hKIFL 11 +S-trityl-L-cysteine derivative + ADP + Mg<br />
-
**[[6vpp]] – DmKlp61F + tubulin + GTP + GDP + Mg – Cryo EM<br />
+
**[[3wpn]] – hKIFL 11 +inhibitor <br />
-
**[[6vpo]] – DmKlp61F + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
+
**[[2uyi]], [[2uym]], [[2gm1]], [[2pg2]], [[2fme]], [[2x7d]], [[2x7c]], [[2ieh]], [[3cjo]], [[2g1q]], [[2fl2]], [[2fl6]], [[1yrs]], [[2q2y]], [[2fky]], [[2q2z]], [[3k3b]], [[2x7e]], [[4a50]], [[4a51]], [[3zcw]], [[6g6y]], **[[6g6z]], [[6hkx]], [[6hky]] - hKIF11+inhibitor +ADP + Mg<br />
-
**[[6b0i]] – DmKlp10A + tubulin + GTP + GDP + ANP + Mg – Cryo EM<br />
+
**[[4bxn]], [[4as7]] – hKIFL 11+inhibitor +ADP + Cd<br />
 +
**[[3l9h]] – hKIFL 11+inhibitor +ADP <br />
 +
**[[4zhi]], [[8yhh]] – hKIFL 11 MD +ADP<br />
 +
**[[1x88]], [[1q0b]] – hKIFL 11 +Mg + ADP+monastrol <br />
 +
**[[4ap0]], [[4a5y]] – hKIFL 11 +MgADP + ispinesib + Mg<br />
 +
**[[3hqd]] – hKIFL 11 +AMPPNP+Mg<br />
 +
**[[1ii6]], [[4a1z]], [[4a28]] – hKIFL11 +ADP+Mg<br />
 +
**[[4zca]], [[6tle]], [[6trl]], [[6y1i]] – hKIFL 11 (mutant) +ADP+Mg<br />
 +
**[[3k5e]] – hKIFL 11 +ADP+enastrol + Mg<br />
 +
**[[4aqv]], [[4aqw]] – hKIFL 11 (mutant) + tubulin + GDP + GTP + Mg – Cryo EM<br />
 +
**[[4ck5]], [[4ck6]], [[4ck7]] – hKIFL 11 (mutant) + tubulin + ADP + GDP + GTP + Mg – Cryo EM<br />
 +
**[[6ta3]], [[6tiw]] – hKIFL 11 MD (mutant) + tubulin + G2P + quinolin derivative + Mg – Cryo EM<br />
 +
**[[6ta4]] – hKIFL 11 MD + tubulin + G2P + ANP + Mg – Cryo EM<br />
 +
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
 +
**[[6s8m]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP – Cryo EM<br />
 +
**[[9ikb]] – CeKIFL 11 + CeKIFL 20 + KAP <br />
-
*KIF11 or kinesin-5 or Eg5
+
*KIF11
-
**[[4b7b]] - hKIF11 (mutant) + ADP + Co + Cd <br />
+
**[[5mm4]], [[5mm7]] – UmKIF + tubulin + GDP + GTP + ANP + taxol – Ustilago maydis – Cryo EM<br />
-
**[[3ken]], [[2wog]], [[2x2r]], [[2xae]], [[4bbg]] - hKIF11 +S-trityl-L-cysteine derivative + ADP + Mg<br />
+
-
**[[3wpn]] - hKIF11 +inhibitor <br />
+
-
**[[2uyi]], [[2uym]], [[2gm1]], [[2pg2]], [[2fme]], [[2x7d]], [[2x7c]], [[2ieh]], [[3cjo]], [[2g1q]], [[2fl2]], [[2fl6]], [[1yrs]], [[2q2y]], [[2fky]], [[2q2z]], [[3k3b]], [[2x7e]], [[4a50]], [[4a51]], [[3zcw]], [[6g6y]], [[6g6z]], [[6hkx]], [[6hky]] - hKIF11+inhibitor +ADP + Mg<br />
+
-
**[[4bxn]], [[4as7]] - hKIF11+inhibitor +ADP + Cd<br />
+
-
**[[3l9h]] - hKIF11+inhibitor +ADP <br />
+
-
**[[4zhi]] – hKIF11 MD +ADP<br />
+
-
**[[1x88]], [[1q0b]] - hKIF11 +Mg + ADP+monastrol <br />
+
-
**[[4ap0]], [[4a5y]] - hKIF11 +MgADP + ispinesib + Mg<br />
+
-
**[[3hqd]] - hKIF11 +AMPPNP+Mg<br />
+
-
**[[1ii6]], [[4a1z]], [[4a28]] - hKIF11 +ADP+Mg<br />
+
-
**[[4zca]], [[6tle]], [[6trl]], [[6y1i]] - hKIF11 (mutant) +ADP+Mg<br />
+
-
**[[3k5e]] - hKIF11 +ADP+enastrol + Mg<br />
+
-
**[[6zpi]] – hKIF11 MD + tubulin + GDP + GTP + Mg – Cryo EM<br />
+
-
**[[4aqv]], [[4aqw]] – hKIF11 (mutant) + tubulin + GDP + GTP + Mg – Cryo EM<br />
+
-
**[[4ck5]], [[4ck6]], [[4ck7]] – hKIF11 (mutant) + tubulin + ADP + GDP + GTP + Mg – Cryo EM<br />
+
-
**[[6ta3]], [[6tiw]] – hKIF11 MD (mutant) + tubulin + G2P + quinolin derivative + Mg – Cryo EM<br />
+
-
**[[6ta4]] – hKIF11 MD + tubulin + G2P + ANP + Mg – Cryo EM<br />
+
-
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – KIF MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
+
-
**[[6s8m]] – fyKIFCut7 MD + tubulin + GDP + GTP + ANP – Cryo EM<br />
+
-
**[[5mm4]], [[5mm7]] – UmKIF + tubulin + GDP + GTP + ANP + taxol – ''Ustilago maydis'' – Cryo EM<br />
+
**[[7nb8]] – PfKIF MD + tubulin + GTP + G2P – ''Plasmodium falciparum'' – Cryo EM<br />
**[[7nb8]] – PfKIF MD + tubulin + GTP + G2P – ''Plasmodium falciparum'' – Cryo EM<br />
**[[7nba]] – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM<br />
**[[7nba]] – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM<br />
 +
 +
* KIF-like 12
 +
 +
**[[7x4n]] – CeKIFL 12 MD + tubulin + darpin + GDP + GTP + ANP – Cryo EM<br />
*KIF13A, KIF13B or kinesin-3
*KIF13A, KIF13B or kinesin-3
-
**[[2cow]] – hKIF13B CAP-gly domain – NMR<br />
 
**[[3gbj]] – hKIF13B MD+ADP <br />
**[[3gbj]] – hKIF13B MD+ADP <br />
-
**[[2cjo]] – hKIF13+inhibitor 30<br />
+
**[[5b64]] – mKIF13B MBS domain + MAGUK<br />
-
**[[3fm8]] – hKIF13B FHA domain + centaurin-alpha-1<br />
+
-
**[[3md8]] – hKIF13B FHA domain + centaurin-alpha-1 + IP4<br />
+
-
**[[5djo]] – mKIF13A CC1-FHA domain <br />
+
-
**[[5djn]] – mKIF13A coiled-coil domain (mutant)<br />
+
-
**[[5b64]] – mKIF13B + MAGUK<br />
+
**[[3kin]], [[2kin]] – rKIF MD <br />
**[[3kin]], [[2kin]] – rKIF MD <br />
**[[6a1z]] – rKIF13B<br />
**[[6a1z]] – rKIF13B<br />
**[[5zbs]], [[6a20]], [[7d8v]] – rKIF13B (mutant)<br />
**[[5zbs]], [[6a20]], [[7d8v]] – rKIF13B (mutant)<br />
**[[7d8v]] – rKIF13B (mutant) + ADP<br />
**[[7d8v]] – rKIF13B (mutant) + ADP<br />
-
**[[5zbr]] – rKIF13B + AMPPNP<br />
+
**[[5zbr]] – rKIF13B MD + AMPPNP<br />
-
*KIF14 or kinesin-3
+
* KIF-like 13B
-
**[[6wwe]], [[6wwi]], [[6wwt]] – hKIF14 MD + Tubulin + GTP + GDP – Cryo EM<br />
+
**[[2cow]] – hKIFL 13B CAP-gly domain – NMR<br />
-
**[[6wwf]], [[6wwh]], [[6wwg]], [[6wwj]], [[6wwk]], [[6wwl]], [[6wwm]], [[6wwn]], [[6wwo]], [[6wwp]], [[6wwq]], [[6wwr]], [[6wws]], [[6wwu]], [[6wwv]], [[7lvq]], [[7lvr]] – mKIF14 MD + Tubulin + nucleotides – Cryo EM<br />
+
**[[3fm8]] – hKIFL 13B FHA domain + centaurin-alpha-1<br />
-
**[[1f9t]], [[1f9u]], [[1f9v]], [[1f9w]], [[3kar]] - yKar3 MD (mutant) – yeast<br />
+
**[[5djo]] – mKIFL 13A CC1-FHA domain <br />
-
**[[4etp]] - yKar3 MD (mutant) + VIK1<br />
+
**[[5djn]] – mKIFL 13A coiled-coil domain (mutant)<br />
-
*KIF15 or kinesin-12
+
*KIF14
-
**[[4bn2]] – hKIF15 MD<br />
+
**[[8yue]] – DmKIF14 + Tubulin + ADP – Cryo EM<br />
-
**[[7ryp]] – hKIF15 MD + KIF-binding protein – Cryo EM<br />
+
**[[8yy2]], [[8yy3]], [[8yy4]], [[8yy5]] – DmKIF14 (mutant) + Tubulin + GTP + GDP + ADP – Cryo EM<br />
-
*KIF16B or kinesin-3
+
*KIF-like 14 or kinesin-3
-
**[[2v14]] – hKIF16B<br />
+
**[[6wwe]], [[6wwi]], [[6wwt]] – hKIF14L MD + Tubulin + GTP + GDP – Cryo EM<br />
-
**[[6ee0]] – hKIF16B PX domain 1026-1156<br />
+
**[[6wwf]], [[6wwh]], [[6wwg]], [[6wwj]], [[6wwk]], [[6wwl]], [[6wwm]], [[6wwn]], [[6wwo]], [[6wwp]], [[6wwq]], [[6wwr]], [[6wws]], [[6wwu]], [[6wwv]], [[7lvq]], [[7lvr]] – mKIF14L MD + Tubulin + nucleotides – Cryo EM<br />
-
*KIF18A, KIF18B or kinesin-8
+
*KIF-like Kar3
-
**[[3lre]] - hKIF18A MD <br />
+
**[[1f9t]], [[1f9u]], [[1f9v]], [[1f9w]], [[3kar]] – yKIFL Kar3 MD (mutant) – yeast<br />
-
**[[5oam]] - hKIF18A MD + tubulin + GTP<br />
+
**[[4etp]] – yKIFL Kar3 MD (mutant) + VIK1<br />
-
**[[5ocu]] - hKIF18A MD + tubulin + GTP + GDP + ANP<br />
+
-
**[[5ogc]] - hKIF18A MD + tubulin + GTP + GDP + taxol<br />
+
-
**[[7rsi]] – hKIF18A MD + KIF-binding protein + ADP – Cryo EM<br />
+
-
*KIF19A or kinesin-8
+
*KIF-like 15 or kinesin-12
-
**[[5gsy]] – mKIF19A MD + GDP<br />
+
**[[4bn2]] – hKIFL 15 MD<br />
-
**[[5gsz]] – mKIF19A MD + ADP<br />
+
**[[7ryp]] – hKIFL 15 MD + KIF-binding protein – Cryo EM<br />
 +
**[[6zpi]] – hKIFL 15 MD + tubulin + GDP + GTP + Mg – Cryo EM<br />
-
*KIF20A, KIF20B or kinesin-6
+
*KIF-like 16B or kinesin-3
-
**[[6yip]] – hKIF20A coiled coil domain 596-668 <br />
+
**[[2v14]], [[6ee0]] – hKIFL 16B PX homology domain 1179-1312<br />
-
**[[5nd3]] – mKIF20A MD + tubulin <br />
+
-
**[[5nd2]], [[5nd4]] – mKIF20A MD + tubulin + ADP <br />
+
-
**[[5nd7]] – mKIF20A MD + tubulin + AMPPNP <br />
+
-
**[[5lef]] – mKIF20A residues 603-665 + RAB-6 <br />
+
-
**[[5x3e]] - KLP MD - Caenorhabditis elegans<br />
+
-
*KIF21A, KIF21B or kinesin-4
+
*KIF-like 18A or kinesin-8
-
**[[5d3a]] – hKIF21A coiled coil domain 938-1017 <br />
+
**[[3lre]] – hKIFL 18A MD <br />
-
**[[7klj]] – hKIF21A WD-repeat domain 1324-1640 <br />
+
**[[5oam]] – hKIFL 18A MD + tubulin + GTP<br />
 +
**[[5ocu]] – hKIFL 18A MD + tubulin + GTP + GDP + ANP<br />
 +
**[[9di0]] – hKIFL 18A MD + tubulin + GTP + GDP + ATP – Cryo EM<br />
 +
**[[5ogc]] – hKIFL 18A MD + tubulin + GTP + GDP + taxol<br />
 +
**[[7rsi]] – hKIFL 18A MD + KIF-binding protein + ADP – Cryo EM<br />
-
*KIF22 or kinesin-10
+
*KIF-like 19A or kinesin-8
-
**[[2edu]] – hKIF22 C-terminal – NMR<br />
+
**[[5gsy]] – mKIFL 19A MD + GDP<br />
-
**[[6nje]] – hKIF22 MD +ADP<br />
+
**[[5gsz]] – mKIFL 19A MD + ADP<br />
 +
 
 +
*KIF-like 20A or kinesin-6
 +
 
 +
**[[6yip]] – hKIFL 20A coiled coil domain 596-668 <br />
 +
**[[8bjs]] – mKIFL 20A 55-510<br />
 +
**[[5nd3]] – mKIFL 20A MD + tubulin <br />
 +
**[[5nd2]], [[5nd4]] – mKIFL 20A MD + tubulin + ADP <br />
 +
**[[5nd7]] – mKIFL 20A MD + tubulin + AMPPNP <br />
 +
**[[8f18]], [[8f1a]] – mKIFL 20A MD + tubulin + GDP + GTP <br />
 +
**[[5lef]] – mKIFL 20A residues 603-665 + RAB-6 <br />
 +
**[[5x3e]] - CeKIFL MD <br />
 +
 
 +
*KIF-like 21A or kinesin-4
 +
 
 +
**[[5d3a]] – hKIFL 21A coiled coil domain 938-1017 <br />
 +
**[[7klj]] – hKIFL 21A WD-repeat domain 1324-1640 <br />
 +
 
 +
*KIF-like 22 or kinesin-10
 +
 
 +
**[[2edu]] – hKIFL 22 C-terminal – NMR<br />
 +
**[[6nje]] – hKIFL 22 MD +ADP<br />
*KIF23 or kinesin-6
*KIF23 or kinesin-6
-
**[[3vhx]] – hKIF23 794-911 + ADP-ribosylation factor 6 <br />
+
**[[3vhx]] – hKIFL 23 794-911 + ADP-ribosylation factor 6 <br />
-
**[[2ncd]], [[1cz7]] – DmKIF MD non-claret disjuctional (NCD) dimer – ''Drosophila melanogaster'' <br />
+
**[[2ncd]], [[1cz7]] – DmKIF MD non-claret disjuctional (NCD) dimer <br />
-
**[[2y5w]], [[2y65]] - DmKIF MD<br />
+
-
**[[4pxt]], [[4pxu]] – DmKIF MD (mutant)<br />
+
-
**[[1n6m]] – DmKIF MD+FNL<br />
+
**[[3l1c]] – DmNCD (mutant)<br />
**[[3l1c]] – DmNCD (mutant)<br />
 +
**[[1ry6]] – PfKIF MD <br />
**[[1ry6]] – PfKIF MD <br />
**[[7nba]] – PfKlF + tubulin + GTP + G2P + ANP + Mg – Cryo EM<br />
**[[7nba]] – PfKlF + tubulin + GTP + G2P + ANP + Mg – Cryo EM<br />
Line 196: Line 256:
**[[6fv0]] – mKLC1 TPR domain + nanobody<br />
**[[6fv0]] – mKLC1 TPR domain + nanobody<br />
**[[5ojf]] – mKLC2 TPR domain <br />
**[[5ojf]] – mKLC2 TPR domain <br />
-
**[[3zfw]], [[5fjy]], [[6ejn]], [[6swu]] - mKLC2 TPR domain + peptide<br />
+
**[[3zfw]], [[5fjy]], [[6ejn]], [[6swu]] - mKLC2 TPR domain + peptide<br />
-
+
*NOD
*NOD
Line 203: Line 263:
**[[3dcb]] - DmNOD catalytic core domain+AMPPNP + Mg<br />
**[[3dcb]] - DmNOD catalytic core domain+AMPPNP + Mg<br />
**[[3dco]] - DmNOD catalytic core domain+ cTubulin + ADP + GDP + GTP + Mg<br />
**[[3dco]] - DmNOD catalytic core domain+ cTubulin + ADP + GDP + GTP + Mg<br />
 +
**[[3pxn]] - DmNOD catalytic core domain+ADP + Mn<br />
}}
}}
- 
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Kinesin

Updated on 23-October-2025


Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Michal Harel

Retrieved from "http://52.214.119.220/wiki/index.php/Kinesin_3D_Structures"
Personal tools