1l1p

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[[Image:1l1p.jpg|left|200px]]
 
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==Solution Structure of the PPIase Domain from E. coli Trigger Factor==
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The line below this paragraph, containing "STRUCTURE_1l1p", creates the "Structure Box" on the page.
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<StructureSection load='1l1p' size='340' side='right'caption='[[1l1p]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1l1p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L1P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l1p OCA], [https://pdbe.org/1l1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l1p RCSB], [https://www.ebi.ac.uk/pdbsum/1l1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l1p ProSAT], [https://www.topsan.org/Proteins/BSGI/1l1p TOPSAN]</span></td></tr>
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{{STRUCTURE_1l1p| PDB=1l1p | SCENE= }}
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</table>
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== Function ==
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'''Solution Structure of the PPIase Domain from E. coli Trigger Factor'''
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[https://www.uniprot.org/uniprot/TIG_ECOLI TIG_ECOLI] Involved in protein export. Acts as a chaperone by maintaining the newly synthesized secretory and non-secretory proteins in an open conformation. Binds to nascent polypeptide chains via ribosomal protein L23 (PubMed:12226666). Functions as a peptidyl-prolyl cis-trans isomerase in vitro, this activity is dispensible in vivo for chaperone activity.<ref>PMID:8633085</ref> <ref>PMID:8521806</ref> <ref>PMID:14726952</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1L1P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1P OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/1l1p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l1p ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Denisov A]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Ekiel I]]
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[[Category: Denisov, A.]]
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[[Category: Gehring K]]
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[[Category: Ekiel, I.]]
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[[Category: Ghandi S]]
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[[Category: Gehring, K.]]
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[[Category: Kozlov G]]
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[[Category: Ghandi, S.]]
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[[Category: Perreault A]]
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[[Category: Kozlov, G.]]
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[[Category: Trempe J-F]]
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[[Category: Perreault, A.]]
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[[Category: Wong M]]
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[[Category: Trempe, J F.]]
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[[Category: Wong, M.]]
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[[Category: Bsgi]]
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[[Category: Mixed beta-alpha structure]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:26:30 2008''
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Current revision

Solution Structure of the PPIase Domain from E. coli Trigger Factor

PDB ID 1l1p

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