This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8pae
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8pae is ON HOLD Authors: Description: Category: Unreleased Structures) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the ectodomain of Atypical Porcine Pestivirus E2 at 1.2A resolution== | |
| - | + | <StructureSection load='8pae' size='340' side='right'caption='[[8pae]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8pae]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atypical_porcine_pestivirus Atypical porcine pestivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PAE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pae OCA], [https://pdbe.org/8pae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pae RCSB], [https://www.ebi.ac.uk/pdbsum/8pae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pae ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A1B1M0D5_9FLAV A0A1B1M0D5_9FLAV] Acts as a cofactor for the NS3 protease activity.[ARBA:ARBA00023576] Packages viral RNA to form a viral nucleocapsid and thereby protects viral RNA. Also plays a role in transcription regulation. Protects the incoming virus against IFN-induced effectors.[ARBA:ARBA00034097] Plays a role in the regulation of viral RNA replication.[ARBA:ARBA00023574] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Atypical porcine pestivirus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aitkenhead H]] | ||
| + | [[Category: EL Omari K]] | ||
| + | [[Category: Stuart DI]] | ||
Current revision
Structure of the ectodomain of Atypical Porcine Pestivirus E2 at 1.2A resolution
| |||||||||||
