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8pat
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8pat is ON HOLD Authors: Compain, G., Monsarrat, C., Blagojevic, J., Brillet, K., Dumas, P., Hammann, P., Kuhn, L., Martiel, I., Engilberge, S., Oli...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3.== | |
| - | + | <StructureSection load='8pat' size='340' side='right'caption='[[8pat]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8pat]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PAT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23P:3-(PROPANOYLAMINO)-L-ALANINE'>23P</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ALC:2-AMINO-3-CYCLOHEXYL-PROPIONIC+ACID'>ALC</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pat OCA], [https://pdbe.org/8pat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pat RCSB], [https://www.ebi.ac.uk/pdbsum/8pat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pat ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/C3SLM2_ECOLX C3SLM2_ECOLX] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hammann | + | [[Category: Blagojevic J]] |
| - | [[Category: | + | [[Category: Brillet K]] |
| - | [[Category: | + | [[Category: Burnouf D]] |
| - | [[Category: | + | [[Category: Compain G]] |
| - | [[Category: | + | [[Category: Dumas P]] |
| + | [[Category: Engilberge S]] | ||
| + | [[Category: Guichard G]] | ||
| + | [[Category: Hammann P]] | ||
| + | [[Category: Kuhn L]] | ||
| + | [[Category: Martiel I]] | ||
| + | [[Category: Monsarrat C]] | ||
| + | [[Category: Olieric V]] | ||
| + | [[Category: Wolff P]] | ||
Current revision
Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3.
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Categories: Escherichia coli | Large Structures | Blagojevic J | Brillet K | Burnouf D | Compain G | Dumas P | Engilberge S | Guichard G | Hammann P | Kuhn L | Martiel I | Monsarrat C | Olieric V | Wolff P
