7g06
From Proteopedia
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| - | ==Crystal Structure of human FABP4 in complex with 5-(chloromethyl)-2-phenyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one== | + | ==Crystal Structure of human FABP4 in complex with 5-(chloromethyl)-2-phenyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, i.e. SMILES c1cccc(c1)C1=NN2C(=N1)NC(=CC2=O)CCl with IC50=28 microM== |
<StructureSection load='7g06' size='340' side='right'caption='[[7g06]], [[Resolution|resolution]] 1.26Å' scene=''> | <StructureSection load='7g06' size='340' side='right'caption='[[7g06]], [[Resolution|resolution]] 1.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7g06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G06 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7g06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G06 FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WJ8: | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.26Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WJ8:5-(chloromethyl)-2-phenyl-4~{H}-[1,2,4]triazolo[1,5-a]pyrimidin-7-one'>WJ8</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g06 OCA], [https://pdbe.org/7g06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g06 RCSB], [https://www.ebi.ac.uk/pdbsum/7g06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g06 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g06 OCA], [https://pdbe.org/7g06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g06 RCSB], [https://www.ebi.ac.uk/pdbsum/7g06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g06 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Current revision
Crystal Structure of human FABP4 in complex with 5-(chloromethyl)-2-phenyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, i.e. SMILES c1cccc(c1)C1=NN2C(=N1)NC(=CC2=O)CCl with IC50=28 microM
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