1l6h

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[[Image:1l6h.jpg|left|200px]]
 
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==Solution Structure of Plant nsLTP2 purified from Rice (oryza Sativa)==
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The line below this paragraph, containing "STRUCTURE_1l6h", creates the "Structure Box" on the page.
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<StructureSection load='1l6h' size='340' side='right'caption='[[1l6h]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1l6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L6H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l6h OCA], [https://pdbe.org/1l6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l6h RCSB], [https://www.ebi.ac.uk/pdbsum/1l6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l6h ProSAT]</span></td></tr>
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{{STRUCTURE_1l6h| PDB=1l6h | SCENE= }}
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</table>
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== Function ==
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'''Solution Structure of Plant nsLTP2 purified from Rice (oryza Sativa)'''
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[https://www.uniprot.org/uniprot/NLTPX_ORYSJ NLTPX_ORYSJ] Transfer lipids across membranes. May play a role in plant defense or in the biosynthesis of cuticle layers.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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The three-dimensional structure of rice nonspecific lipid transfer protein (nsLTP2) has been solved for the first time. The structure of nsLTP2 was obtained using 813 distance constraints, 30 hydrogen bond constraints, and 19 dihedral angle constraints. Fifteen of the 50 random simulated annealing structures satisfied all of the constraints and possessed good nonbonded contacts. The novel three-dimensional fold of rice nsLTP2 contains a triangular hydrophobic cavity formed by three prominent helices. The four disulfide bonds required for stabilization of the nsLTP2 structure show a different pattern of cysteine pairing compared with nsLTP1. The C terminus of the protein is very flexible and forms a cap over the hydrophobic cavity. Molecular modeling studies suggested that the hydrophobic cavity could accommodate large molecules with rigid structures, such as sterols. The positively charged residues on the molecular surface of nsLTP2 are structurally similar to other plant defense proteins.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l6/1l6h_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1L6H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L6H OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l6h ConSurf].
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Solution structure of plant nonspecific lipid transfer protein-2 from rice (Oryza sativa)., Samuel D, Liu YJ, Cheng CS, Lyu PC, J Biol Chem. 2002 Sep 20;277(38):35267-73. Epub 2002 May 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12011089 12011089]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Oryza sativa]]
[[Category: Oryza sativa]]
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[[Category: Single protein]]
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[[Category: Lyu P-C]]
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[[Category: Lyu, P C.]]
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[[Category: Samuel D]]
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[[Category: Samuel, D.]]
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[[Category: Lipid transfer]]
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[[Category: Nsltp2]]
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[[Category: Plant ltp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 23:35:35 2008''
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Current revision

Solution Structure of Plant nsLTP2 purified from Rice (oryza Sativa)

PDB ID 1l6h

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