6ota

<table><tr><td colspan='2'>[[6ota]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_textile Conus textile]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OTA FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ota FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ota OCA], [https://pdbe.org/6ota PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ota RCSB], [https://www.ebi.ac.uk/pdbsum/6ota PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ota ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/CA1A_CONTE CA1A_CONTE] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin inhibits rat alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=3.5 nM), rat alpha-7/CHRNA7 (IC(50)=392 nM) nAChR, and the L.stagnalis soluble acetylcholine receptor (all tested without hydroxyproline).<ref>PMID:17660751</ref>

== References ==

<references/>

[[Category: Conus textile]]