LDL receptor

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:41, 26 October 2025) (edit) (undo)
 
(One intermediate revision not shown.)
Line 22: Line 22:
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*hLDLR ligand-binding domain
+
*hLDLR ligand-binding domain;Repeats - LB1 20-67; LB2 55-104; LB4 144-195; LB5 196-232; LB6 234-272; LB7 274-313
**[[1ldl]] – hLDLR LB1 - human - NMR<br />
**[[1ldl]] – hLDLR LB1 - human - NMR<br />
Line 72: Line 72:
**[[3m0c]] – hLDLR LBD,EGFP, oligosaccharide-rich, membrane-spanning domains + proprotein convertase subtilisin/kexin 9<br />
**[[3m0c]] – hLDLR LBD,EGFP, oligosaccharide-rich, membrane-spanning domains + proprotein convertase subtilisin/kexin 9<br />
**[[3p5b]], [[3p5c]] – hLDLR EGFP, oligosaccharide-rich, domains + proprotein convertase subtilisin/kexin 9<br />
**[[3p5b]], [[3p5c]] – hLDLR EGFP, oligosaccharide-rich, domains + proprotein convertase subtilisin/kexin 9<br />
 +
**[[9bdt]], [[9coo]] – hLDLR + apolipoprotein B + legobody + nanobody + MBP – Cryo EM<br />
 +
**[[9bd8]], [[9bde]] – hLDLR + apolipoprotein B – Cryo EM<br />
 +
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of human LDLR LBD and EGFP domains (magenta) complex with proprotein convertase subtilisin/kexin 9-CoA reductase (cyan and green) and Ca+2 ions (green) (PDB entry 3m0c)

Drag the structure with the mouse to rotate

3D structures of LDL receptor

Updated on 26-October-2025

References

  1. Goldstein JL, Brown MS. The LDL receptor. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):431-8. doi:, 10.1161/ATVBAHA.108.179564. PMID:19299327 doi:http://dx.doi.org/10.1161/ATVBAHA.108.179564
  2. Mak YT, Pang CP, Tomlinson B, Zhang J, Chan YS, Mak TW, Masarei JR. Mutations in the low-density lipoprotein receptor gene in Chinese familial hypercholesterolemia patients. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1600-5. PMID:9763532

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Personal tools