This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8jpe
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8jpe is ON HOLD Authors: Duan, J., Liu, H., Zhao, F., Yuan, Q., Ji, Y., Xu, H.E. Description: Focused refinement structure of Galpha(q) in NTSR1-GR...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes== | |
| - | + | <StructureSection load='8jpe' size='340' side='right'caption='[[8jpe]], [[Resolution|resolution]] 2.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpe OCA], [https://pdbe.org/8jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpe RCSB], [https://www.ebi.ac.uk/pdbsum/8jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpe ProSAT]</span></td></tr> |
| - | [[Category: Duan | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: Liu | + | [https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Sturge-Weber syndrome;Phakomatosis cesioflammea;Uveal melanoma;Familial multiple nevi flammei. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
| - | [[Category: Yuan | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Duan J]] | ||
| + | [[Category: Ji Y]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Xu HE]] | ||
| + | [[Category: Yuan Q]] | ||
| + | [[Category: Zhao F]] | ||
Current revision
Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes
| |||||||||||
Categories: Homo sapiens | Large Structures | Duan J | Ji Y | Liu H | Xu HE | Yuan Q | Zhao F
