8jpe

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m (Protected "8jpe" [edit=sysop:move=sysop])
Current revision (05:30, 9 August 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8jpe is ON HOLD
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==Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes==
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<StructureSection load='8jpe' size='340' side='right'caption='[[8jpe]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
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Authors: Duan, J., Liu, H., Zhao, F., Yuan, Q., Ji, Y., Xu, H.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPE FirstGlance]. <br>
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Description: Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Xu, H.E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpe OCA], [https://pdbe.org/8jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpe RCSB], [https://www.ebi.ac.uk/pdbsum/8jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpe ProSAT]</span></td></tr>
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[[Category: Duan, J]]
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</table>
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[[Category: Zhao, F]]
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== Disease ==
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[[Category: Liu, H]]
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[https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Sturge-Weber syndrome;Phakomatosis cesioflammea;Uveal melanoma;Familial multiple nevi flammei. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Yuan, Q]]
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== Function ==
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[[Category: Ji, Y]]
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[https://www.uniprot.org/uniprot/GNAQ_HUMAN GNAQ_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Duan J]]
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[[Category: Ji Y]]
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[[Category: Liu H]]
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[[Category: Xu HE]]
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[[Category: Yuan Q]]
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[[Category: Zhao F]]

Current revision

Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes

PDB ID 8jpe

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