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8jr9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8jr9 is ON HOLD Authors: Zhao, L., He, Q., Yuan, Q., Gu, Y., He, X., Shan, H., Li, J., Wang, K., Li, Y., Hu, W., Wu, K., Shen, J., Xu, H.E. Descrip...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R)== | |
| - | + | <StructureSection load='8jr9' size='340' side='right'caption='[[8jr9]], [[Resolution|resolution]] 2.57Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8jr9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JR9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.57Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KHF:1-[3,5-dimethyl-4-[2-[[4-oxidanylidene-2-[4-(trifluoromethyloxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-5,5-dimethyl-imidazolidine-2,4-dione'>KHF</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jr9 OCA], [https://pdbe.org/8jr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jr9 RCSB], [https://www.ebi.ac.uk/pdbsum/8jr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jr9 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: He | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Li | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Wang | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Gu Y]] |
| - | [[Category: | + | [[Category: He Q]] |
| + | [[Category: He X]] | ||
| + | [[Category: Hu W]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Li Y]] | ||
| + | [[Category: Shan H]] | ||
| + | [[Category: Shen J]] | ||
| + | [[Category: Wang K]] | ||
| + | [[Category: Wu K]] | ||
| + | [[Category: Xu HE]] | ||
| + | [[Category: Yuan Q]] | ||
| + | [[Category: Zhao L]] | ||
Current revision
Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R)
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Categories: Homo sapiens | Large Structures | Mus musculus | Gu Y | He Q | He X | Hu W | Li J | Li Y | Shan H | Shen J | Wang K | Wu K | Xu HE | Yuan Q | Zhao L
